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Host Pathogen Interactions Ontology
| Preferred Name | anatomical structure | |
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| Definitions |
Comment in Foundational Model of Anatomy(FMA): CR comments: 1. Inherent 3D shape implies that it is maximally connected; also there is no supertype "maximally connected material anatomical entity" in AT. 2. It is not sufficient to state that it is generated by the organism's own genome; tumors are also generated by the organism's own genome; different ones than the anatomical structures that bear them, or from which they are derived. Specifying morphogenesis constrains the genes that come into play. 3. Arrangement of parts is also important, because rouleaux etc have a shape. Old definition: Material anatomical entity which has inherent 3D shape; is generated by coordinated expression of the organism's own genome; its parts are spatially related to one another in patterns determined by coordinated gene expression. OM proposed definition: Material physical anatomical entity which has inherent 3D shape; the maximal aggregation of constitutional parts is generated by coordinated expression of the organism's own structural genes; consists of parts that are anatomical structures; spatially related to one another in patterns determined by coordinated gene expression. Examples: heart, right ventricle, mitral valve, myocardium, endothelium, lymphocyte, fibroblast, thorax, cardiovascular system, hemoglobin, T cell receptor, structural gene. |
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| ID |
http://www.semanticweb.org/ontologies/2010/5/22/Ontology1277229984000.owl#HPI:0000037 |
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| comment |
Comment in Foundational Model of Anatomy(FMA): CR comments: 1. Inherent 3D shape implies that it is maximally connected; also there is no supertype "maximally connected material anatomical entity" in AT. 2. It is not sufficient to state that it is generated by the organism's own genome; tumors are also generated by the organism's own genome; different ones than the anatomical structures that bear them, or from which they are derived. Specifying morphogenesis constrains the genes that come into play. 3. Arrangement of parts is also important, because rouleaux etc have a shape. Old definition: Material anatomical entity which has inherent 3D shape; is generated by coordinated expression of the organism's own genome; its parts are spatially related to one another in patterns determined by coordinated gene expression. OM proposed definition: Material physical anatomical entity which has inherent 3D shape; the maximal aggregation of constitutional parts is generated by coordinated expression of the organism's own structural genes; consists of parts that are anatomical structures; spatially related to one another in patterns determined by coordinated gene expression. Examples: heart, right ventricle, mitral valve, myocardium, endothelium, lymphocyte, fibroblast, thorax, cardiovascular system, hemoglobin, T cell receptor, structural gene.
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| hasDbXref |
CARO:0000003 FMA:67135
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| hasDefinition |
Material anatomical entity which is generated by coordinated expression of the organism's own genes that guide its morphogenesis; has inherent 3D shape; its parts are connected and spatially related to one another in patterns determined by coordinated gene expression. Examples: heart, right ventricle, mitral valve, myocardium, endothelium, lymphocyte, fibroblast, thorax, cardiovascular system, hemoglobin, T cell receptor.
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| hasSynonym |
biological structure
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| identifier |
HPI:0000037
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| label |
anatomical structure
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| prefLabel |
anatomical structure
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| source |
Foundational Model of Anatomy(FMA).
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