loading...| Preferred Name | heart | |
| Synonyms |
branchial heart cardium vertebrate heart chambered heart |
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| Definitions |
A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706 |
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| ID |
http://purl.obolibrary.org/obo/UBERON_0000948 |
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| comment |
Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706 |
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| axiom_lost_from_external_ontology |
relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO] |
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| database_cross_reference |
galen:Heart SCTID:302509004 CALOHA:TS-0445 MAT:0000036 XAO:0000064 TAO:0000114 MESH:D006321 EHDAA2:0000738 BTO:0000562 BILA:0000020 VHOG:0000276 NCIT:C12727 MIAA:0000036 UMLS:C0018787 ZFA:0000114 EFO:0000815 Wikipedia:Heart EMAPA:16105 AAO:0010210 EHDAA:420 EV:0100018 FMA:7088 GAID:174 MA:0000072 |
|
| definition |
A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. |
|
| depiction |
https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb |
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| external_definition |
Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO] Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO] |
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| has_exact_synonym |
vertebrate heart chambered heart |
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| has_narrow_synonym |
branchial heart |
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| has_obo_namespace |
uberon |
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| has_related_synonym |
cardium |
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| has_relational_adjective |
cardiac |
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| homology_notes |
As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG] |
|
| id |
UBERON:0000948 |
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| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas http://purl.obolibrary.org/obo/uberon/core#efo_slim http://purl.obolibrary.org/obo/uberon/core#organ_slim http://purl.obolibrary.org/obo/uberon/core#vertebrate_core http://purl.obolibrary.org/obo/uberon/core#major_organ |
|
| label |
heart |
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| never_in_taxon | ||
| notation |
UBERON:0000948 |
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| part_of |
http://purl.obolibrary.org/obo/UBERON_0015410 http://purl.obolibrary.org/obo/UBERON_0000467 http://purl.obolibrary.org/obo/UBERON_0002100 |
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| preferred label |
heart |
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| prefLabel |
heart |
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| RO_0002175 | ||
| treeView |
http://purl.obolibrary.org/obo/UBERON_0015410 http://purl.obolibrary.org/obo/UBERON_0000467 http://purl.obolibrary.org/obo/UBERON_0002100 |
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| subClassOf |