loading...| Preferred Name | spleen | |
| Synonyms |
lien |
|
| Definitions |
The organ that functions to filter blood and to store red corpuscles and platelets. |
|
| ID |
http://purl.obolibrary.org/obo/UBERON_0002106 |
|
| database_cross_reference |
NCIT:C12432 EMAPA:18767 SCTID:181279003 XAO:0000328 MIAA:0000085 ZFA:0000436 VHOG:0000120 MESH:D013154 galen:Spleen CALOHA:TS-0956 BTO:0001281 UMLS:C0037993 MAT:0000085 EFO:0000869 TAO:0000436 AAO:0010395 Wikipedia:Spleen EV:0100055 FMA:7196 GAID:1289 MA:0000141 |
|
| definition |
The organ that functions to filter blood and to store red corpuscles and platelets. |
|
| depiction |
https://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg https://cdn.humanatlas.io/digital-objects/ref-organ/spleen-male/v1.3/assets/3d-vh-m-spleen.glb https://cdn.humanatlas.io/digital-objects/ref-organ/spleen-female/v1.3/assets/3d-vh-f-spleen.glb |
|
| develops_from | ||
| external_definition |
An organ involved in red blood cell filtration and immune response.[AAO] |
|
| function_notes |
It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells |
|
| has_obo_namespace |
uberon |
|
| has_related_synonym |
lien |
|
| has_relational_adjective |
lienal splenic |
|
| homology_notes |
With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG] |
|
| id |
UBERON:0002106 |
|
| in taxon | ||
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas http://purl.obolibrary.org/obo/uberon/core#efo_slim http://purl.obolibrary.org/obo/uberon/core#organ_slim http://purl.obolibrary.org/obo/uberon/core#vertebrate_core |
|
| label |
spleen |
|
| located in | ||
| notation |
UBERON:0002106 |
|
| part_of |
http://purl.obolibrary.org/obo/UBERON_0002390 |
|
| prefLabel |
spleen |
|
| present_in_taxon | ||
| taxon_notes |
Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96) In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron |
|
| treeView |
http://purl.obolibrary.org/obo/UBERON_0002390 http://purl.obolibrary.org/obo/UBERON_0006293 |
|
| disjointWith | ||
| subClassOf |
http://purl.obolibrary.org/obo/UBERON_0004177 |