Preferred Name |
spleen |
|
Synonyms |
lien |
|
Definitions |
the organ that functions to filter blood and to store red corpuscles and platelets |
|
ID |
http://purl.obolibrary.org/obo/UBERON_0002106 |
|
database_cross_reference |
http://linkedlifedata.com/resource/umls/id/C0037993 http://www.snomedbrowser.com/Codes/Details/181279003 http://en.wikipedia.org/wiki/Spleen MAT:0000085 EMAPA:18767 EV:0100055 MESH:A15.382.520.604.713 ISBN:0-683-40008-8 AAO:0010395 BTO:0001281 EFO:0000869 MIAA:0000085 OpenCyc:Mx4rvVjgw5wpEbGdrcN5Y29ycA TAO:0000436 VHOG:0000120 MP:0000689 CALOHA:TS-0956 UMLS:C0037993 GAID:1289 galen:Spleen NCIT:C12432 XAO:0000328 FMA:7196 MA:0000141 ZFA:0000436 |
|
date_retrieved |
2012-09-17 2012-06-20 |
|
definition |
the organ that functions to filter blood and to store red corpuscles and platelets |
|
depicted by |
http://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg |
|
external_class |
AAO:0010395 VHOG:0000120 |
|
external_definition |
An organ involved in red blood cell filtration and immune response.[AAO] |
|
function_notes |
It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells |
|
has_obo_namespace |
uberon |
|
has_related_synonym |
lien |
|
has_relational_adjective |
splenic lienal |
|
homology_notes |
With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG] |
|
id |
UBERON:0002106 |
|
imported from |
http://purl.obolibrary.org/obo/uberon/releases/2018-11-25/uberon.owl |
|
in_subset |
http://purl.obolibrary.org/obo/uberon/core#efo_slim http://purl.obolibrary.org/obo/uberon/core#organ_slim http://purl.obolibrary.org/obo/uberon/core#vertebrate_core |
|
label |
spleen |
|
notation |
UBERON:0002106 |
|
ontology |
VHOG AAO |
|
prefLabel |
spleen |
|
source |
http://www.ncbi.nlm.nih.gov/pubmed/20959416 ISBN:978-0781765190 Paul WE, Fundamental Immunology (2008) p.94 AAO:BMZ ncithesaurus:Spleen |
|
taxon_notes |
Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96) In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron |
|
subClassOf |