loading...| Preferred Name | spleen | |
| Synonyms |
lien |
|
| Definitions |
The organ that functions to filter blood and to store red corpuscles and platelets. |
|
| ID |
http://purl.obolibrary.org/obo/UBERON_0002106 |
|
| altLabel |
lien |
|
| ccf_is_provisional |
false |
|
| ccf_part_of |
http://purl.obolibrary.org/obo/UBERON_0002390 http://purl.obolibrary.org/obo/UBERON_0013702 |
|
| ccf_pref_label |
spleen |
|
| definition |
The organ that functions to filter blood and to store red corpuscles and platelets. |
|
| depiction |
https://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Spleen.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Spleen.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Spleen.glb |
|
| external_definition |
An organ involved in red blood cell filtration and immune response.[AAO] |
|
| function_notes |
It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells |
|
| has related synonym |
lien |
|
| has_obo_namespace |
uberon |
|
| has_relational_adjective |
splenic lienal |
|
| homology_notes |
With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG] |
|
| id |
UBERON:0002106 |
|
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas http://purl.obolibrary.org/obo/uberon/core#efo_slim http://purl.obolibrary.org/obo/uberon/core#organ_slim http://purl.obolibrary.org/obo/uberon/core#vertebrate_core |
|
| isDefinedBy | ||
| label |
spleen |
|
| notation |
UBERON:0002106 |
|
| prefLabel |
spleen |
|
| present in taxon | ||
| taxon_notes |
Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96) In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron |
|
| xRef |
MAT:0000085 EMAPA:18767 EV:0100055 AAO:0010395 SCTID:181279003 BTO:0001281 EFO:0000869 MIAA:0000085 TAO:0000436 VHOG:0000120 CALOHA:TS-0956 UMLS:C0037993 Wikipedia:Spleen GAID:1289 galen:Spleen NCIT:C12432 XAO:0000328 FMA:7196 MESH:D013154 MA:0000141 ZFA:0000436 |
|
| subClassOf |
http://purl.obolibrary.org/obo/UBERON_0004177 |