Preferred Name |
Plasma |
|
Synonyms |
|
|
ID |
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass1f13ad1c_444c_4d72_84d5_64b7e332dda6 |
|
Chinese |
血浆 |
|
European_expert_opinion |
脑电图和血药浓度有助于对患者进行管理。VPA血药浓度可以作为指导,但其个体差异很大,缺乏关于母体血药浓度与MCMs风险之间的关系的证据。建议将VPA水平根据临床反应维持在推荐治疗范围以下。脑电图并不是可靠的指标。 Patient management will vary across diferent national health systems. EEG recordings and plasma drug concentration measurements, for example, may be part of national epilepsy management guidelines. Plasma valproate levels may be used as a guide, but interindividual doses vary widely and defnitive data on the association between maternal plasma drug levels and MCM risks are lacking. The target valproate level can be maintained below the recommended therapeutic range, depending on clinical response. EEG recordings are not a reliable biomarker of clinical response, but they can be of help when interpreted by an epilepsy specialist. Family planning is important in patients taking AEDs. Toledo M, Mostacci B, Bosak M, Jedrzejzak J, Thomas RH, Salas-Puig J, Biraben A, Schmitz B. Expert opinion: use of valproate in girls and women of childbearing potential with epilepsy: recommendations and alternatives based on a review of the literature and clinical experience-a European perspective. J Neurol. 2020 Apr 1. doi: 10.1007/s00415-020-09809-0. Epub ahead of print. PMID: 32239268. |
|
MESH_Definition |
The residual portion of BLOOD that is left after removal of BLOOD CELLS by CENTRIFUGATION without prior BLOOD COAGULATION. |
|
NCIt_Definition |
Plasma is the fluid (noncellular) portion of the circulating blood, as distinguished from the serum that is the fluid portion of the blood obtained by removal of the fibrin clot and blood cells after coagulation. |
|
prefLabel |
Plasma |
|
Synonyms |
Plasma Blood Blood plasma Plasmas blood plasma Blood Plasma Plasma Plasmas Blood PLASMA Portion of plasma plasma Blood Plasmas Blood plasma (product) Plasma (substance) |
|
subClassOf |