loading...| Preferred Name |
Progressive supranuclear palsy |
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| Synonyms |
PSP |
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| Definitions |
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al (source : MSH) |
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| ID |
http://doe-generated-ontology.com/OntoAD#C0038868 |
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| altLabel |
PSP Ophtalmoplégie supranucléaire STEELE RICHARDSON OLSZEWSKI DIS Steele-Richardson-Olszewski Disease Supranuclear Palsy, Progressive Progressive Supranuclear Ophthalmoplegia PSP Prog supranuclear palsy Ophtalmoplégie supranucléaire progressive Heterogeneous system degeneration Paralysie supranucléaire évolutive Steele-Richardson-Olszewski Syndrome Syndrome de Steele-Richardson-Olszewski Maladie de Steele-Ridcharson PSNP1 PSP Progressive supranuclear palsy SUPRANUCLEAR PALSY, PROGRESSIVE, 1 Maladie de Steele-Richardson-Olszewski Steele-Richardson-Olszew syndr PSP (Paralysie Supranucléaire Progressive) Steele-Richardson-Olszewski Progressive supranuclear ophth Nuchal dystonia-dementia syndrome Ophtalmoplégie supranucléaire progressive [maladie de Steele-Richardson-Olszewski] |
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| definition |
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al (source : MSH) maladie dégénérative du système nerveux central caractérisé par les difficultés de balance; les troubles MOTILITÉ OCULAIRES (¤slsupranuclear¤sl ophtalmoplégie ); dysarthrie ; l'ingurgitation des difficultés; et DYSTONIE axial. Le commencement est en général dans la cinquième décade et la progression de maladie se produit plus de plusieurs années. Les conclusions de Pathologique incluent la dégénération neurofibrillaire et la perte neuronal dans mésencéphale dorsal; NUCLÉUS de sous-thalamique ; N (source : CISMeF) |
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| disease_has_associated_anatomic_site | ||
| has_associated_morphology | ||
| has_finding_site | ||
| has_manifestation |
http://doe-generated-ontology.com/OntoAD#C0242422 http://doe-generated-ontology.com/OntoAD#C0233565 http://doe-generated-ontology.com/OntoAD#C0013362 http://doe-generated-ontology.com/OntoAD#C0085400 http://doe-generated-ontology.com/OntoAD#C0085632 http://doe-generated-ontology.com/OntoAD#C0085639 http://doe-generated-ontology.com/OntoAD#C0026837 http://doe-generated-ontology.com/OntoAD#C0542476 |
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| has_severity | ||
| hiddenLabel |
ParalysieSupranucléaireProgressive ProgressiveSupranuclearPalsy |
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| prefixIRI |
OntoAD:C0038868 |
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| prefLabel |
Paralysie supranucléaire progressive Progressive supranuclear palsy |
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| subClassOf |
http://doe-generated-ontology.com/OntoAD#C2062713 http://doe-generated-ontology.com/OntoAD#C0004782 http://doe-generated-ontology.com/OntoAD#C0949664 |