Cell Line Ontology

Last uploaded: June 20, 2026
Details
Acronym CLO
Visibility Public
Description The Cell Line Ontology (CLO) is a community-based ontology in domain of biological cell lines with a focus on permanent cell lines from culture collections. Upper ontology structures that frame the skeleton of CLO include Basic Formal Ontology and Relation Ontology. Cell lines contained in CLO are associated with terms from other ontologies such as Cell Type Ontology, NCBI Taxonomy, and Ontology for Biomedical Investigation. A common design pattern for the cell line is used to model cell lines and their attributes, the Jurkat cell line provides ane xample. Currently CLO contains over 36,000 cell line entries obtained from ATCC, HyperCLDB, Coriell, and bymanual curation. The cell lines are derived from 194 cell types, 656 anatomical entries, and 217 organisms. The OWL-based CLO is machine-readable and can be used in various applications., The Cell Line Ontology (CLO) is a community-based ontology of cell lines. The CLO is developed to unify publicly available cell line entry data from multiple sources to a standardized logically defined format based on consensus design patterns.
Status Production
Format OWL
Categories
Taxonomic Classification
Phenotype
Anatomy
Experimental Conditions
All Organisms
Biological Process
Vocabularies
Biomedical Resources
Cell
Groups
OBO Foundry
Bibliographic reference
http://www.jbiomedsem.com/content/5/1/37
http://www.jbiomedsem.com/content/5/1/37
Contact
Oliver He ([email protected])
Sirarat Sarntivijai ([email protected])
Creation date
June 20, 2026
Deprecated
false See more...
Documentation
https://code.google.com/p/clo-ontology/ See more...
Homepage
http://www.clo-ontology.org/ See more...
License
Notes
Citation: Sarntivijai S, Lin Y, Xiang Z, Meehan TF, Diehl AD, Vempati UD, Schürer TC, Pang C, Malone J, Parkinson H, Liu Y, Takatsuki T, Saijo K, Masuya H, Nakamura Y, Brush MH, Haendel MA, Zheng J, Stoeckert CJ, Peters B, Mungall CJ, Carey TE, States DJ, Athey BD, He Y. CLO: The Cell Line Ontology. Journal of Biomedical Semantics. 2014, 5:37. doi:10.1186/2041-1480-5-37. PMID: 25852852. PMCID: PMC4387853. See more...
Object creation date property
http://purl.org/dc/elements/1.1/created
http://purl.org/dc/elements/1.1/created
Object modification date property
http://purl.org/dc/elements/1.1/modified
http://purl.org/dc/elements/1.1/modified
Root of obsolete branch
http://www.geneontology.org/formats/oboInOwl#ObsoleteClass
http://www.geneontology.org/formats/oboInOwl#ObsoleteClass
Subject
An ontology for the domain of cell lines and cell line cells See more...
Submission date
June 20, 2026
Version IRI
http://purl.obolibrary.org/obo/clo/releases/2026-06-19/clo.owl
http://purl.obolibrary.org/obo/clo/releases/2026-06-19/clo.owl
Version information
2026-06-19 See more...
uri
http://purl.obolibrary.org/obo/clo.owl
http://purl.obolibrary.org/obo/clo.owl
Submissions
Version Released Uploaded Downloads
2026-06-19 (Parsed, Indexed, Metrics, Annotator) 06/20/2026 06/20/2026 OWL | CSV | RDF/XML | Diff
2.1.188 (Archived) 06/28/2024 06/28/2024 OWL | Diff
2.1.178 (Archived) 03/21/2022 03/21/2022 OWL | Diff
2.1.162 (Archived) 02/10/2019 02/10/2019 OWL | Diff
2.1.142 (Archived) 01/17/2019 01/17/2019 OWL | Diff
2.1.141 (Archived) 10/15/2018 10/15/2018 OWL | Diff
2.1.135 (Archived) 02/07/2018 02/07/2018 OWL | Diff
2.1.106 (Archived) 05/31/2017 05/31/2017 OWL | Diff
2.1.104 (Archived) 05/30/2017 05/30/2017 OWL | Diff
2.1.99 (Archived) 05/23/2017 05/23/2017 OWL | Diff
2.1.98 (Archived) 05/21/2017 05/21/2017 OWL | Diff
2.1.91 (Archived) 04/21/2017 04/21/2017 OWL | Diff
2.1.90 (Archived) 02/06/2017 02/06/2017 OWL | Diff
2.1.83 (Archived) 08/31/2016 08/31/2016 OWL | Diff
2.1.83 (Archived) 07/07/2016 07/07/2016 OWL | Diff
2.1.79 (Archived) 05/04/2016 05/04/2016 OWL | Diff
2.1.76 (Archived) 04/30/2016 04/30/2016 OWL | Diff
2.1.67 (Archived) 04/27/2016 04/27/2016 OWL | Diff
2.1.66 (Archived) 04/25/2016 04/25/2016 OWL | Diff
2.1.65 (Archived) 04/22/2016 04/22/2016 OWL | Diff
2.1.64 (Archived) 04/21/2016 04/21/2016 OWL | Diff
2.1.63 (Archived) 10/13/2015 10/13/2015 OWL | Diff
2.1.63 (Archived) 08/20/2015 08/20/2015 OWL | Diff
2.1.64 (Archived) 08/19/2015 04/25/2015 OWL | Diff
2.1.59 (Archived) 11/06/2013 02/21/2014 OWL | Diff
2.1.59 (Archived) 11/06/2013 02/21/2014 OWL | Diff
2.1.59 (Archived) 11/06/2013 02/20/2014 OWL
2.1.59 (Archived) 11/06/2013 02/20/2014 OWL
2.1.52 (Archived) 11/06/2013 11/06/2013 OWL | Diff
2.1.52 (Archived) 10/21/2013 10/21/2013 OWL | Diff
2.1.52 (Archived) 10/21/2013 10/21/2013 OWL | Diff
2.1.52 (Archived) 10/10/2013 10/10/2013 OWL
2.1.52 (Archived) 08/05/2013 08/05/2013 OWL
2.1.52 (Archived) 07/04/2013 07/04/2013 OWL
2.1.46 (Archived) 06/19/2013 06/19/2013 OWL
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2.1.43 (Archived) 06/16/2013 06/16/2013 OWL
2.1.42 (Archived) 06/13/2013 06/13/2013 OWL
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2.1.32 (Archived) 05/23/2013 05/23/2013 OWL
2.1.30 (Archived) 05/06/2013 05/06/2013 OWL
2.1.29 (Archived) 04/26/2013 04/26/2013 OWL
2.1.28 (Archived) 04/07/2013 04/26/2013 OWL
2.1.28 (Archived) 04/07/2013 04/07/2013 OWL
unknown (Archived) 04/06/2013 04/06/2013 OWL
2.1.28 (Archived) 03/29/2013 03/29/2013 OWL
2.1.25 (Archived) 03/28/2013 03/28/2013 OWL
2.1.24 (Archived) 03/27/2013 03/27/2013 OWL
2.1.22 (Archived) 03/22/2013 03/22/2013 OWL
2.1.19 (Archived) 03/15/2013 03/15/2013 OWL
2.1.05 (Archived) 02/26/2013 02/26/2013 OWL
2.1.03 (Archived) 01/11/2013 01/11/2013 OWL
2.1.03 (Archived) 01/10/2013 01/10/2013 OWL
2.1.04 (Archived) 11/16/2012 11/16/2012 OWL
unknown (Archived) 11/15/2012 11/15/2012 OWL
2.1.04 (Archived) 09/20/2012 09/20/2012 OWL
2.1.03 (Archived) 09/20/2012 09/20/2012 OWL
2.0.36 (Archived) 09/20/2012 09/20/2012 OWL
2.0.36 (Archived) 07/13/2012 07/23/2012 OWL
2.0.36 (Archived) 07/13/2012 07/19/2012 OWL
2.0.36 (Archived) 07/13/2012 07/13/2012 OWL
2.0.35 (Archived) 07/13/2012 07/13/2012 OWL
2.0.35 (Archived) 07/13/2012 07/12/2012 OWL
2.0.27 (Archived) 03/10/2011 03/10/2011 OWL
2.0.26 (Archived) 03/09/2011 03/10/2011 OWL
1 (Archived) 02/29/2008 07/08/2009 OWL
more...
Views of CLO

No views of CLO available

Metrics
Classes 40,852
Individuals 30
Properties 98
Maximum depth 24
Maximum number of children 21,698
Average number of children 22
Classes with a single child 769
Classes with more than 25 children 69
Classes with no definition 7,411
Visits
Projects using CLO

Beta Cell Genomics database

BioAssay Express

HiTS

ISA software suite