National Cancer Institute Thesaurus

Last uploaded: September 30, 2019
Preferred Name

Arginine

Synonyms

L-Arginine

arginine

Arg

Arginine

Amino-5-guanidino-pentanoic acid

ARGININE

L-arginine

Definitions

An essential amino acid in juvenile humans, Arginine is a complex amino acid, often found at active site in proteins and enzymes due to its amine-containing side chain. Arginine may prevent or treat heart and circulatory diseases, combat fatigue, and stimulate the immune system. It also boosts production of nitric oxide, relaxing blood vessels, and treating angina and other cardiovascular problems. Arginine is also an important intermediate in the urea cycle and in detoxification of nitrogenous wastes. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62008

ALT_DEFINITION

Amino acid with side chain -CH2CH2CH2NH-C(NH)NH2.

One of the twenty common amino acids (building blocks of proteins). Arginine is being studied as a nutritional supplement in the treatment and prevention of cancer and other conditions.

CAS_Registry

74-79-3

CHEBI_ID

CHEBI:16467

Chemical_Formula

C6H14N4O2

code

C62008

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

Contributing_Source

CRCH

CTRP

FDA

DEFINITION

An essential amino acid in juvenile humans, Arginine is a complex amino acid, often found at active site in proteins and enzymes due to its amine-containing side chain. Arginine may prevent or treat heart and circulatory diseases, combat fatigue, and stimulate the immune system. It also boosts production of nitric oxide, relaxing blood vessels, and treating angina and other cardiovascular problems. Arginine is also an important intermediate in the urea cycle and in detoxification of nitrogenous wastes. (NCI04)

Display_Name

Arginine

Essential_Amino_Acid

Y

FDA_UNII_Code

94ZLA3W45F

FULL_SYN

L-Arginine

arginine

Arg

Arginine

Amino-5-guanidino-pentanoic acid

ARGININE

L-arginine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29606

INFOODS

ARG_G

label

Arginine

Legacy_Concept_Name

Arginine_Base

Macronutrient

Y

NSC_Code

206269

Nutrient

Y

Preferred_Name

Arginine

prefixIRI

ncit:C62008

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0003765

Unit

g

USDA_ID

511

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68442

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http://bmi.utah.edu/ontologies/hfontology/C0003765 HFO LOOM
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http://purl.obolibrary.org/obo/SO_0001451 ORTH LOOM
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http://purl.bioontology.org/ontology/SNMI/F-64090 SNMI LOOM
http://www.semanticweb.org/tome/ontologies/2015/7/Richfields#arginine ISO-FOOD LOOM
http://purl.jp/bio/10/gmo/GMO_001203 GMO LOOM
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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.095.104 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0003765 OCHV LOOM
http://purl.bioontology.org/ontology/CSP/0866-4938 CRISP LOOM
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http://sbmi.uth.tmc.edu/ontology/ochv#1425 OCHV LOOM
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http://purl.obolibrary.org/obo/CHEBI_29016 BIOMODELS LOOM
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http://purl.obolibrary.org/obo/CHEBI_29016 DRON LOOM
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