Preferred Name | apoptosis | |
Synonyms |
type I programmed cell death apoptotic program signaling (initiator) caspase activity apoptotic cell death programmed cell death by apoptosis apoptotic programmed cell death |
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Definitions |
A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell. |
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ID |
http://purl.obolibrary.org/obo/GO_0006915 |
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database_cross_reference |
Reactome:1483323 Reactome:1392809 Reactome:1483249 Reactome:1252953 Reactome:1497027 Reactome:1326456 Reactome:1327003 Reactome:1417869 Reactome:1532709 Reactome:1299325 Reactome:1372799 Reactome:1532666 Reactome:1417797 Wikipedia:Apoptosis Reactome:1526973 Reactome:1393372 Reactome:1471362 Reactome:1253559 Reactome:1280425 Reactome:193648 Reactome:1279984 Reactome:1298877 Reactome:1471339 Reactome:205043 Reactome:1450896 Reactome:1514414 Reactome:1280422 Reactome:1373286 Reactome:1352572 Reactome:1450375 Reactome:1299256 Reactome:1253485 Reactome:1496989 Reactome:1353097 Reactome:1353095 Reactome:1373284 Reactome:1514376 Reactome:1280424 Reactome:1450958 Reactome:1526930 Reactome:1353098 Reactome:1536054 Reactome:109581 Reactome:1393299 Reactome:1253487 Reactome:1327001 Reactome:1299258 Reactome:205025 Reactome:1521264 Reactome:1417383 Reactome:1327004 |
|
definition |
A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell. |
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has_alternative_id |
GO:0008632 |
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has_exact_synonym |
apoptotic cell death programmed cell death by apoptosis apoptotic programmed cell death |
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has_narrow_synonym |
type I programmed cell death apoptotic program |
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has_obo_namespace |
biological_process |
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has_related_synonym |
signaling (initiator) caspase activity |
|
id |
GO:0006915 |
|
label |
apoptosis |
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notation |
GO:0006915 |
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prefLabel |
apoptosis |
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treeView | ||
subClassOf |