Gene Ontology Extension

Last uploaded: June 24, 2011
Preferred Name

apoptosis
Synonyms

type I programmed cell death

apoptotic program

signaling (initiator) caspase activity

apoptotic cell death

programmed cell death by apoptosis

apoptotic programmed cell death

Definitions

A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell.

ID

http://purl.obolibrary.org/obo/GO_0006915

database_cross_reference

Reactome:1483323

Reactome:1392809

Reactome:1483249

Reactome:1252953

Reactome:1497027

Reactome:1326456

Reactome:1327003

Reactome:1417869

Reactome:1532709

Reactome:1299325

Reactome:1372799

Reactome:1532666

Reactome:1417797

Wikipedia:Apoptosis

Reactome:1526973

Reactome:1393372

Reactome:1471362

Reactome:1253559

Reactome:1280425

Reactome:193648

Reactome:1279984

Reactome:1298877

Reactome:1471339

Reactome:205043

Reactome:1450896

Reactome:1514414

Reactome:1280422

Reactome:1373286

Reactome:1352572

Reactome:1450375

Reactome:1299256

Reactome:1253485

Reactome:1496989

Reactome:1353097

Reactome:1353095

Reactome:1373284

Reactome:1514376

Reactome:1280424

Reactome:1450958

Reactome:1526930

Reactome:1353098

Reactome:1536054

Reactome:109581

Reactome:1393299

Reactome:1253487

Reactome:1327001

Reactome:1299258

Reactome:205025

Reactome:1521264

Reactome:1417383

Reactome:1327004

definition

A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell.

has_alternative_id

GO:0008632

has_exact_synonym

apoptotic cell death

programmed cell death by apoptosis

apoptotic programmed cell death

has_narrow_synonym

type I programmed cell death

apoptotic program

has_obo_namespace

biological_process

has_related_synonym

signaling (initiator) caspase activity

id

GO:0006915

label

apoptosis

notation

GO:0006915

prefLabel

apoptosis

treeView

http://purl.obolibrary.org/obo/GO_0012501

subClassOf

http://purl.obolibrary.org/obo/GO_0012501

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/GO_0006915 UBERON SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 CL SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 OBA SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 NIGO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 CLO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 PLANP SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 GCBO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 CCONT SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 FOVT SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 HOIP SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 RBO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 OBI_BCGO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 EFO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 XPO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 PHAGE SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 CMPO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 COVID-19 SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 PCL SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 PATO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 BAO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 NIFDYS SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 BERO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 HHEAR SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 TXPO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 INO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 UPHENO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 FTC SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 CHIRO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 ECAO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 KTAO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 FYPO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 REGN_GO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 HINO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 MAXO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 GO SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 ZP SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 AISM SAME_URI
http://purl.obolibrary.org/obo/GO_0006915 NMDCO SAME_URI
http://scai.fraunhofer.de/HuPSON#SCAIVPH_00000304 HUPSON LOOM
http://purl.org/obo/owl/GO#GO_0006915 NPO LOOM
http://purl.org/obo/owl/GO#GO_0006915 BIOMODELS LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/20663007 SNOMEDCT LOOM
http://localhost/plosthes.2017-1#5488 PLOSTHES LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D017209 RH-MESH LOOM
http://scai.fraunhofer.de/CSEO#CSEO_00000992 CSEO LOOM
http://cbo.biocomplexity.indiana.edu/svn/cbo/trunk/CBO_1_1_2.owl#Apoptosis CBO LOOM
http://purl.bioontology.org/ontology/MESH/D017209 MESH LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Apoptosis APAONTO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17557 NCIT LOOM
http://www.co-ode.org/ontologies/galen#Apoptosis GALEN LOOM
http://www.semanticweb.org/ontologies/2008/8/MultiscaleSkinPhysiologyOntology.owl#Apoptosis SPO LOOM
http://www.stanford.edu/~coulet/phare.owl#Apoptosis PHARE LOOM
http://purl.obolibrary.org/obo/OMIT_0017600 OMIT LOOM
http://purl.obolibrary.org/obo/HINO_0016253 HINO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#G04.299.139.160 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#17920 OCHV LOOM
http://scai.fraunhofer.de/CSEO#CSEO_00000043 CSEO LOOM
http://purl.jp/bio/4/id/200906039143928462 IOBC LOOM
http://purl.obolibrary.org/obo/MPATH_3 MPATH LOOM
http://purl.obolibrary.org/obo/MPATH_3 BMONT LOOM
http://www.projecthalo.com/aura#Apoptosis AURA LOOM
urn:agi-pathway:uuid-be878e67-d551-45ea-a23d-6170599173a9 BPT LOOM
http://purl.bioontology.org/ontology/CSP/4001-0010 CRISP LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_fa2ff13e_2ae6_45aa_8d84_dd2441fbb074 STO-DRAFT LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_fa2ff13e_2ae6_45aa_8d84_dd2441fbb074 CVAO LOOM
http://www.semanticweb.org/ADMO#apoptosis ADMO LOOM
http://www.pepathway.org/peo/1.2#Apoptosis PE-O LOOM
http://purl.obolibrary.org/obo/MESH_D017209 BERO LOOM
http://purl.obolibrary.org/obo/APO_0000155 APO LOOM
http://purl.obolibrary.org/obo/APO_0000155 UPHENO LOOM
http://doe-generated-ontology.com/OntoAD#C0162638 ONTOAD LOOM
http://purl.bioontology.org/ontology/SNMI/M-54250 SNMI LOOM
http://purl.obolibrary.org/obo/NCIT_C17557 BERO LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571345044435366089 ACVD_ONTOLOGY LOOM
http://regenbase.org/ontology#RB_0000040 RB LOOM
http://purl.bioontology.org/ontology/MEDDRA/10059512 MEDDRA LOOM
http://scai.fraunhofer.de/PWDICT#ID1019 PTS LOOM
http://purl.obolibrary.org/obo/GO_0006915 NIGO LOOM