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Alzheimer Disease Map Ontology
Last uploaded:
April 21, 2020
| Acronym | ADMO |
| Visibility | Public |
| Description | Alzheimer’s disease (AD) pathophysiology is still imperfectly understood and current paradigms have not led to curative outcome. Omics technologies offer great promises for improving our understanding and generating new hypotheses. However, integration and interpretation of such data pose major challenges, calling for adequate knowledge models. AlzPathway is a disease map that gives a detailed and broad account of AD pathophysiology. However, AlzPathway lacks formalism, which can lead to ambiguity and misinterpretation. Ontologies are an adequate framework to overcome this limitation, through their axiomatic definitions and logical reasoning prop-erties. We introduce the AD Map Ontology (ADMO), an ontological upper model based on systems biology terms. We then propose to convert AlzPathway into an ontology and to integrate it into ADMO. |
| Status | Beta |
| Format | OWL |
| Contact | Henry Vincent, vincent.henry@inria.fr Colliot Olivier, olivier.colliot@upmc.fr |
| Categories | Biological Process, Human |
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