Preferred Name |
endothelial cell |
|
Synonyms |
endotheliocyte |
|
Definitions |
From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. The main type of cell found in the inside lining of blood vessels, lymph vessels, and the heart. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. |
|
ID |
http://purl.obolibrary.org/obo/CL_0000115 |
|
comment |
From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. The main type of cell found in the inside lining of blood vessels, lymph vessels, and the heart. |
|
database_cross_reference |
CALOHA:TS-0278 BTO:0001176 FMA:66772 |
|
definition source |
BTO:0001176 CL:0000115 |
|
has_exact_synonym |
endotheliocyte |
|
has_obo_namespace |
cell |
|
imported from | ||
label |
endothelial cell |
|
prefixIRI |
CL:0000115 |
|
prefLabel |
endothelial cell |
|
see also |
EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000467 |
|
term editor |
James Malone |
|
textual definition |
An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. |
|
subClassOf |
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