Cell Line Ontology

Last uploaded: June 28, 2024
Preferred Name

fibroblast
Synonyms

primary dermal fibroblast

mouse embryonic fibroblast

Definitions

A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. A large, flat, oval cell found in connective tissue and responsible for the formation of fibers. A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms.

ID

http://purl.obolibrary.org/obo/CL_0000057

comment

These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.

A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.

A large, flat, oval cell found in connective tissue and responsible for the formation of fibers.

A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms.

alternative term

primary dermal fibroblast

mouse embryonic fibroblast

database_cross_reference

BTO:0000452

VHOG:0001482

CALOHA:TS-0362

FMA:63877

definition source

BTO:0000452

NIFSTD:nlx_cell_20090201

CL:0000057

develops_from

http://purl.obolibrary.org/obo/CL_0000134

has_obo_namespace

cell

imported from

http://purl.obolibrary.org/obo/cl.owl

http://purl.obolibrary.org/obo/uberon.owl

label

fibroblast

prefixIRI

CL:0000057

prefLabel

fibroblast

see also

URI: http://www.ebi.ac.uk/cellline#fibroblast

EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000496

term editor

Tomasz Adamusiak

James Malone

textual definition

A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.

treeView

http://purl.obolibrary.org/obo/CL_0000134

subClassOf

http://purl.obolibrary.org/obo/CARO_0000000

http://purl.obolibrary.org/obo/CL_0002320

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CL_0000057 CL SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 PDRO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 UBERON SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 OBI SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 AEO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 GCBO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 CCONT SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 FOVT SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 HOIP SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 CHEAR SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 NGBO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 ONE SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 RBO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 OBI_BCGO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 EFO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 XPO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 EGO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 DOID SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 SP SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 PCL SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 MONDO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 PATO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 NIFDYS SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 BERO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 EFO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 HHEAR SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 DDSS SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 TXPO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 HRA SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 UPHENO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 OBI_IEE SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 ECAO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 KTAO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 MAXO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 EHDAA2 SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 AISM SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 NMDCO SAME_URI
http://purl.obolibrary.org/obo/CL_0000057 OBA SAME_URI
http://purl.obolibrary.org/obo/CL_2000067 HRA LOOM
http://purl.obolibrary.org/obo/CL_2000066 HRA LOOM
http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Cell.owl#nlx_cell_20090201 NIFCELL LOOM
http://purl.obolibrary.org/obo/CL_1000308 HRA LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/52547004 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/NCIT_C12482 BERO LOOM
http://purl.obolibrary.org/obo/CL_0000057 CL LOOM
http://purl.obolibrary.org/obo/CL_0000057 PDRO LOOM
http://purl.obolibrary.org/obo/CL_0000057 UBERON LOOM
http://purl.obolibrary.org/obo/CL_0000057 OBI LOOM
http://purl.obolibrary.org/obo/CL_0000057 AEO LOOM
http://purl.obolibrary.org/obo/CL_0000057 GCBO LOOM
http://purl.obolibrary.org/obo/CL_0000057 CCONT LOOM
http://purl.obolibrary.org/obo/CL_0000057 FOVT LOOM
http://purl.obolibrary.org/obo/CL_0000057 HOIP LOOM
http://purl.obolibrary.org/obo/CL_0000057 CHEAR LOOM
http://purl.obolibrary.org/obo/CL_0000057 NGBO LOOM
http://purl.obolibrary.org/obo/CL_0000057 ONE LOOM
http://purl.obolibrary.org/obo/CL_0000057 RBO LOOM
http://purl.obolibrary.org/obo/CL_0000057 OBI_BCGO LOOM
http://purl.obolibrary.org/obo/CL_0000057 EFO LOOM
http://purl.obolibrary.org/obo/CL_0000057 XPO LOOM
http://purl.obolibrary.org/obo/CL_0000057 EGO LOOM
http://purl.obolibrary.org/obo/CL_0000057 DOID LOOM
http://purl.obolibrary.org/obo/CL_0000057 SP LOOM
http://purl.obolibrary.org/obo/CL_0000057 PCL LOOM
http://purl.obolibrary.org/obo/CL_0000057 PATO LOOM
http://purl.obolibrary.org/obo/CL_0000057 NIFDYS LOOM
http://purl.obolibrary.org/obo/CL_0000057 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CL_0000057 EFO LOOM
http://purl.obolibrary.org/obo/CL_0000057 HHEAR LOOM
http://purl.obolibrary.org/obo/CL_0000057 DDSS LOOM
http://purl.obolibrary.org/obo/CL_0000057 TXPO LOOM
http://purl.obolibrary.org/obo/CL_0000057 UPHENO LOOM
http://purl.obolibrary.org/obo/CL_0000057 OBI_IEE LOOM
http://purl.obolibrary.org/obo/CL_0000057 NIFSTD LOOM
http://purl.obolibrary.org/obo/CL_0000057 ECAO LOOM
http://purl.obolibrary.org/obo/CL_0000057 KTAO LOOM
http://purl.obolibrary.org/obo/CL_0000057 MAXO LOOM
http://purl.obolibrary.org/obo/CL_0000057 EHDAA2 LOOM
http://purl.obolibrary.org/obo/CL_0000057 AISM LOOM
http://purl.obolibrary.org/obo/CL_0000057 NMDCO LOOM
http://purl.obolibrary.org/obo/CL_0000057 OBA LOOM
http://purl.org/obo/owl/CL#CL_0000057 BIOMODELS LOOM
http://purl.obolibrary.org/obo/ZFA_0009026 ZFA LOOM
http://purl.obolibrary.org/obo/ZFA_0009026 ZP LOOM
http://purl.org/obo/owlapi/fma#FMA_63877 BIOMODELS LOOM
http://www.co-ode.org/ontologies/galen#Fibroblast GALEN LOOM
http://purl.jp/bio/4/id/200906030929190753 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0016030 OCHV LOOM
http://www.semanticweb.org/ontologies/2008/8/MultiscaleSkinPhysiologyOntology.owl#Fibroblast SPO LOOM
http://purl.bioontology.org/ontology/CSP/0729-6107 CRISP LOOM
http://purl.obolibrary.org/obo/LMHA_00169 LUNGMAP_H_CELL LOOM
http://purl.obolibrary.org/obo/CL_0002620 HRA LOOM
http://scai.fraunhofer.de/CSEO#CSEO_00001116 CSEO LOOM
http://purl.obolibrary.org/obo/CL_1000692 HRA LOOM
http://purl.obolibrary.org/obo/LMMA_00169 LUNGMAP_M_CELL LOOM
http://www.projecthalo.com/aura#Fibroblast AURA LOOM
http://purl.obolibrary.org/obo/ID_0000155 BCTEO LOOM
http://www.semanticweb.org/hanfei/ontologies/2020/9/untitled-ontology-1306#Fibroblast COVID-19-ONT-PM LOOM
http://purl.obolibrary.org/obo/TAO_0009026 TAO LOOM
http://purl.obolibrary.org/obo/BTO_0000452 DTO LOOM
http://purl.obolibrary.org/obo/BTO_0000452 BTO LOOM
http://uri.neuinfo.org/nif/nifstd/nlx_cell_20090201 NIFSTD LOOM
http://purl.org/sig/ont/fma/fma63877 FMA LOOM
http://purl.bioontology.org/ontology/LNC/LP7234-0 LOINC LOOM
http://purl.obolibrary.org/obo/VHOG_0001482 VHOG LOOM
http://purl.obolibrary.org/obo/XAO_0003017 XPO LOOM
http://purl.obolibrary.org/obo/XAO_0003017 XAO LOOM
http://purl.bioontology.org/ontology/SNMI/T-1A101 SNMI LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12482 NCIT LOOM