Preferred Name |
fibroblast |
|
Synonyms |
primary dermal fibroblast mouse embryonic fibroblast |
|
Definitions |
These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. A large, flat, oval cell found in connective tissue and responsible for the formation of fibers. A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms. A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. |
|
ID |
http://purl.obolibrary.org/obo/CL_0000057 |
|
comment |
These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. A large, flat, oval cell found in connective tissue and responsible for the formation of fibers. A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms. |
|
alternative term |
primary dermal fibroblast mouse embryonic fibroblast |
|
database_cross_reference |
FMA:63877 BTO:0000452 CALOHA:TS-0362 VHOG:0001482 |
|
definition source |
BTO:0000452 CL:0000057 NIFSTD:nlx_cell_20090201 |
|
develops_from | ||
has_obo_namespace |
cell |
|
imported from | ||
label |
fibroblast |
|
prefixIRI |
CL:0000057 |
|
prefLabel |
fibroblast |
|
see also |
EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000496 |
|
term editor |
James Malone Tomasz Adamusiak |
|
textual definition |
A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. |
|
treeView | ||
subClassOf |
This ontology integrates with OntoloBridge, allowing community users to suggest additions to the public ontology. Complete the template below to submit a term request directly to the ontology maintainer.
Term Label (required)
Suggested term name. If a term can be described with multiple synonyms, only list the preferred name here.
Term description (required)
A brief definition, description, or usage of your suggested term. Additional term synonyms may be listed in this section.
Superclass (required)
The parent term of the suggested term. The parent term should be an existing entry of the current ontology. The superclass can be selected directly from Bioportal's Classes tree viewer.
References (optional)
Provide evidence for the existence of the requested term such as Pubmed IDs of papers or links to other resources that describe the term.
Justification (optional)
Provide any additional information about the requested term here.