loading...| Preferred Name |
Verapamil |
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| Synonyms |
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| ID |
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass5df0ba96_9e76_436e_987c_ddef6612dd7b |
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| Chinese |
维拉帕米 |
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| label |
Verapamil |
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| MESH_Definition |
A calcium channel blocker that is a class IV anti-arrhythmia agent. |
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| NCIt_Definition |
A phenylalkylamine calcium channel blocking agent. Verapamil inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04) |
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| prefLabel |
Verapamil |
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| Synonyms |
Verapamilum Iproveratril alpha-[3-[[2-(34-Dimethoxyphenyl)ethyl]methylamino]propyl]-34-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile Verapamil 52-53-9 Verapamil-containing product Verapamil (substance) Benzeneacetonitrile alpha-(3-((2-(34-dimethoxyphenyl)ethyl)methylamino)propyl)-34-dimethoxy-alpha-(1-methylethyl)- Verapamil SR Vérapamil Product containing verapamil (medicinal product) Verapamilo |
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| subClassOf |