Ontology of Biological Attributes

Last uploaded: March 27, 2024
Preferred Name

endothelial cell

Synonyms
Definitions

From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].

ID

http://purl.obolibrary.org/obo/CL_0000115

comment

From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].

label

endothelial cell

prefixIRI

CL:0000115

prefLabel

endothelial cell

RO_0002175

http://purl.obolibrary.org/obo/NCBITaxon_9606

subClassOf

http://purl.obolibrary.org/obo/CL_0000213

http://purl.obolibrary.org/obo/CL_0002078

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http://purl.obolibrary.org/obo/CL_0000115 GO-PLUS SAME_URI
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http://purl.obolibrary.org/obo/CL_0000115 CHEAR SAME_URI
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http://purl.obolibrary.org/obo/CL_0000115 CHEAR LOOM
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http://purl.obolibrary.org/obo/CL_0000115 NMDCO LOOM
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