National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Receptor Tyrosine Kinase

Synonyms

Tyrosine Receptor Kinase

Tyrosine Kinase Receptor

EGF Receptor-Tyrosine Kinase Family

Receptor Tyrosine Kinase

Receptor-Tyrosine Kinase

Tyrosine Kinase Growth Factor Receptor

EC 2.7.10.1

Receptor-Type Protein-Tyrosine Kinase

Receptor Protein-Tyrosine Kinase

Transmembrane Receptor Protein Tyrosine Kinase

RTK

TKR

TRK

Definitions

A class of membrane receptors that contain protein tyrosine kinase activity. This enzymatic activity is integral to the function of the receptor as a signal transducer; the phosphorylation event alters the functional activity of its protein substrate.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17660

code

C17660

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

A class of membrane receptors that contain protein tyrosine kinase activity. This enzymatic activity is integral to the function of the receptor as a signal transducer; the phosphorylation event alters the functional activity of its protein substrate.

Display_Name

Receptor Tyrosine Kinase

FULL_SYN

Tyrosine Receptor Kinase

Tyrosine Kinase Receptor

EGF Receptor-Tyrosine Kinase Family

Receptor Tyrosine Kinase

Receptor-Tyrosine Kinase

Tyrosine Kinase Growth Factor Receptor

EC 2.7.10.1

Receptor-Type Protein-Tyrosine Kinase

Receptor Protein-Tyrosine Kinase

Transmembrane Receptor Protein Tyrosine Kinase

RTK

TKR

TRK

label

Receptor Tyrosine Kinase

Legacy Concept Name

Receptor_Tyrosine_Kinase

Preferred_Name

Receptor Tyrosine Kinase

prefixIRI

Thesaurus:C17660

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Receptor

UMLS_CUI

C0206364

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18106

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17020

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