National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Protein Tyrosine Kinase

Synonyms

Tyrosine-Protein Kinase

Protein-Tyrosine Kinase

Tyrosine-Specific Protein Kinase

Tyrosine Kinase

Protein Tyrosine Kinase

Tyrosine Protein Kinase

EC 2.7.10

PTK

Definitions

Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand-binding domain, a single transmembrane domain, and an intracellular tyrosine kinase domain; and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (Dictionary of Cell and Molecular Biology Online)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17020

code

C17020

DEFINITION

Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand-binding domain, a single transmembrane domain, and an intracellular tyrosine kinase domain; and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (Dictionary of Cell and Molecular Biology Online)

DesignNote

Formerly 2.7.1.112

FULL_SYN

Tyrosine-Protein Kinase

Protein-Tyrosine Kinase

Tyrosine-Specific Protein Kinase

Tyrosine Kinase

Protein Tyrosine Kinase

Tyrosine Protein Kinase

EC 2.7.10

PTK

label

Protein Tyrosine Kinase

Legacy Concept Name

Protein_Tyrosine_Kinase

Preferred_Name

Protein Tyrosine Kinase

prefixIRI

Thesaurus:C17020

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

UMLS_CUI

C0033681

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17018

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