Preferred Name |
Receptor |
|
Synonyms |
Receptor Protein Receptor receptor |
|
Definitions |
A protein located on the cell surface, or in the cytoplasm, that binds to a specific signaling factor, such as a hormone, antigen, or neurotransmitter, causing a conformational and functional change in the receptor molecule. The ligand-bound receptor then alters its interaction with target molecules, which leads to changes in cellular physiology through modification of the activity of one or more signal transduction pathways. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18106 |
|
ALT_DEFINITION |
A molecule inside or on the surface of a cell that binds to a specific substance and causes a specific physiologic effect in the cell. |
|
code |
C18106 |
|
DEFINITION |
A protein located on the cell surface, or in the cytoplasm, that binds to a specific signaling factor, such as a hormone, antigen, or neurotransmitter, causing a conformational and functional change in the receptor molecule. The ligand-bound receptor then alters its interaction with target molecules, which leads to changes in cellular physiology through modification of the activity of one or more signal transduction pathways. |
|
FULL_SYN |
Receptor Protein Receptor receptor |
|
label |
Receptor |
|
Legacy Concept Name |
Receptor |
|
Preferred_Name |
Receptor |
|
prefixIRI |
Thesaurus:C18106 |
|
Semantic_Type |
Amino Acid, Peptide, or Protein Receptor |
|
UMLS_CUI |
C0597357 |
|
subClassOf |