loading...| Preferred Name |
tuberculosis |
|
| Synonyms |
active tuberculosis tuberculosis disease Kochs disease TB |
|
| Definitions |
A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use. |
|
| ID |
http://purl.obolibrary.org/obo/MONDO_0018076 |
|
| conformsTo |
http://purl.obolibrary.org/obo/mondo/patterns/environmental_stimulus.yaml http://purl.obolibrary.org/obo/mondo/patterns/specific_infectious_disease_by_agent.yaml |
|
| database_cross_reference |
ICD10:A15.A19 DOID:399 NCIT:C3423 COHD:434557 Orphanet:3389 MedDRA:10044755 GARD:0007827 ICD9:017.94 ICD9:017.90 MESH:D014376 SCTID:56717001 UMLS:C0151332 ICD9:017.96 ICD9:017.92 UMLS:C0041296 |
|
| exactMatch |
http://identifiers.org/snomedct/56717001 http://linkedlifedata.com/resource/umls/id/C0151332 http://www.orpha.net/ORDO/Orphanet_3389 http://purl.obolibrary.org/obo/DOID_399 http://linkedlifedata.com/resource/umls/id/C0041296 http://purl.obolibrary.org/obo/NCIT_C3423 |
|
| has exact synonym |
active tuberculosis tuberculosis disease |
|
| has modifier | ||
| has related synonym |
Kochs disease TB |
|
| id |
MONDO:0018076 |
|
| imported from | ||
| in_subset | ||
| label |
tuberculosis |
|
| notation |
MONDO:0018076 |
|
| prefLabel |
tuberculosis |
|
| realized in response to stimulus | ||
| see also |
https://rarediseases.info.nih.gov/diseases/7827/tuberculosis |
|
| textual definition |
A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use. |
|
| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0005550 |