The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Details
Visualization
Notes ( 0 )
Class Mappings ( )

Preferred Name	morphine
Synonyms	(-)-morphine Morphia 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol (1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15-tetraene-10,14-diol morphinum (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL morphium morfina (5alpha,6alpha)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol Morphin (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol C17H19NO3 (5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol Morphine
ID	http://purl.obolibrary.org/obo/CHEBI_17303
activates	http://purl.obolibrary.org/obo/dinto_0760 http://purl.obolibrary.org/obo/dinto_2787 http://purl.obolibrary.org/obo/dinto_3960
AHFScode	84:24.12 28:08.08
altId	CHEBI:7001 CHEBI:44202 CHEBI:25419 CHEBI:14622
ATCCode	N02AA09 S01XA06 G04BE07 R05DA05 N02AA04 N04BC07 N02AA01 D10AX30 R05DA01
CASRN	57-27-2
DBBrand	oms concentrate morphia morphine forte depodur meconium morphitec morphium oramorph sr roxanol ud roxanol 100 l-morphine m.o.s morfina duramorph pf nepenthe epimorph morphinism morphine extra-forte moscontin avinza roxanol dulcontin morphine h.p kadian astramorph pf rescudose msir m-eslon ms/s ms/l duromorph ms contin rms uniserts ospalivina statex drops
DBname	morphine
DBSalt	morphine sulfate
DBSynonym	(-)-morphine heroine hydrochloride d-(-)-morphine o,o'-diacetylmorphine hydrochloride diacetylmorphine hydrochloride morphinum morphina heroin hydrochloride roxanol morphin (-)-heroin hydrochloride diamorphine hydrochloride
Definition	A highly potent opiate analgesic psychoactive drug, morphine acts directly on the central nervous system (CNS) to relieve pain. Morphine has a high potential for addiction; tolerance and both physical and psychological dependence develop rapidly.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000496 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0000395 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000888 http://purl.obolibrary.org/obo/OAE_0001098 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001437 http://purl.obolibrary.org/obo/OAE_0001045 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000617 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001066 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000482 http://purl.obolibrary.org/obo/OAE_0001370 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0001069 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0001025 http://purl.obolibrary.org/obo/OAE_0000677 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000915 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000517 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0000498 http://purl.obolibrary.org/obo/OAE_0001101 http://purl.obolibrary.org/obo/OAE_0000526 http://purl.obolibrary.org/obo/OAE_0001068 http://purl.obolibrary.org/obo/OAE_0000587 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000772 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000533 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000674 http://purl.obolibrary.org/obo/OAE_0000894 http://purl.obolibrary.org/obo/OAE_0000243 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000606 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000194 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000860 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000275 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 http://purl.obolibrary.org/obo/OAE_0000514 http://purl.obolibrary.org/obo/OAE_0001001 http://purl.obolibrary.org/obo/OAE_0000881 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000618 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target	http://purl.obolibrary.org/obo/dinto_0760 http://purl.obolibrary.org/obo/dinto_2787 http://purl.obolibrary.org/obo/dinto_3960
has role	http://purl.obolibrary.org/obo/CHEBI_55322 http://purl.obolibrary.org/obo/CHEBI_35482
InChI	InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
InChIKey	InChIKey=BQJCRHHNABKAKU-KBQPJGBKSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_1440
is metabolised by	http://purl.obolibrary.org/obo/dinto_1890 http://purl.obolibrary.org/obo/dinto_1892 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_1850 http://purl.obolibrary.org/obo/dinto_1848 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_1711 http://purl.obolibrary.org/obo/dinto_0276
is transported by	http://purl.obolibrary.org/obo/dinto_1440
label	morphine
may interact with	http://purl.obolibrary.org/obo/dinto_DB00685 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/dinto_DB06210 http://purl.obolibrary.org/obo/dinto_DB06274
prefixIRI	obo2:CHEBI_17303
prefLabel	morphine
SMILES	[H][C@]12C=C[C@H](O)[C@@H]3Oc4c(O)ccc5C[C@H]1N(C)CC[C@@]23c45 [H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])C=C[C@@H]2O
Synonym	(-)-morphine Morphia 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol (1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15-tetraene-10,14-diol morphinum (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL morphium morfina (5alpha,6alpha)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol Morphin (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol C17H19NO3 (5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol Morphine
xref	CiteXplore:17667569 PDBeChem:MOI CASRN:57-27-2 NIST Chemistry WebBook:57-27-2 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/msc1277.shtml PubChem Compound:5288826 PDB:MOI KEGG COMPOUND:C01516 ChEBI:17303 Beilstein:93704 ChemSpider:4450907 MetaCyc:MORPHINE ChEMBL:106005 Drugs.com:http://www.drugs.com/morphine.html PharmGKB:PA450550 National Drug Code Directory:63629-3789-3 Wikipedia:http://en.wikipedia.org/wiki/Morphine Drugs Product Database (DPD):2245286 PDB:1Q0Y RxList:http://www.rxlist.com/cgi/generic/ms.htm Wikipedia:Morphine CiteXplore:15019787 PubChem Substance:46505161 DrugBank:DB00295
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display

Create mapping

Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_17303	GO-PLUS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	EFO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	OBA	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	OBIB	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	NBO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_17303	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/XCO_0000610	XCO	LOOM
http://purl.obolibrary.org/obo/CHEBI_17303	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_17303	OBA	LOOM
http://purl.obolibrary.org/obo/CHEBI_17303	CHEBI	LOOM
http://purl.bioontology.org/ontology/NDDF/001545	NDDF	LOOM
http://purl.bioontology.org/ontology/VANDF/4017530	VANDF	LOOM
http://purl.jp/bio/4/id/200906019258104039	IOBC	LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02180	MIO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009020	RH-MESH	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018039	PMAPP-PMO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0066814	OCHV	LOOM
http://purl.bioontology.org/ontology/LNC/LP15174-3	LOINC	LOOM
http://bmi.utah.edu/ontologies/peontology/C0026549	RAO	LOOM
http://www.limics.fr/ontologies/ontoparonmed#Morphine	ONTOPARON	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8253	OCHV	LOOM
http://purl.obolibrary.org/obo/NCIT_C62051	BERO	LOOM
http://purl.jp/bio/4/id/200906040525314586	IOBC	LOOM
http://localhost/plosthes.2017-1#9289	PLOSTHES	LOOM
http://www.drugbank.ca/drugs/DB00295	FTC	LOOM
http://purl.obolibrary.org/obo/CHEBI_17303	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_17303	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_17303	OBIB	LOOM
http://purl.obolibrary.org/obo/CHEBI_17303	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_17303	NBO	LOOM
http://purl.obolibrary.org/obo/CHEBI_17303	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_17303	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_17303	NIFSTD	LOOM
http://bmi.utah.edu/ontologies/hfontology/C0026549	HFO	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004293	LOINC	LOOM
http://purl.bioontology.org/ontology/ATC/N02AA01	ATC	LOOM
https://go.drugbank.com/drugs/DB00295	MDM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.723.795.576.571	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.577.249.562.571	RH-MESH	LOOM
http://stirdf.jst.go.jp/id/200907065808619410	IOBC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0026549	OCHV	LOOM
http://purl.obolibrary.org/obo/OMIT_0010065	OMIT	LOOM
http://purl.bioontology.org/ontology/RXNORM/7052	RXNORM	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Morphine	APAONTO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373529000	SNOMEDCT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62051	NCIT	LOOM
http://purl.bioontology.org/ontology/CSP/0092-7466	CRISP	LOOM
http://purl.obolibrary.org/obo/SCDO_0000771	SCDO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.549.686.607.587	RH-MESH	LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00408	OCIMIDO	LOOM
http://www.co-ode.org/ontologies/galen#Morphine	GALEN	LOOM
http://purl.bioontology.org/ontology/SNMI/C-606B0	SNMI	LOOM
http://www.gamuts.net/entity#morphine	GAMUTS	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000145914	NDFRT	LOOM
http://stirdf.jst.go.jp/id/200907025618571184	IOBC	LOOM
http://purl.obolibrary.org/obo/MESH_D009020	BERO	LOOM
http://purl.bioontology.org/ontology/LNC/LA28611-4	LOINC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.497.607.587	RH-MESH	LOOM
http://purl.bioontology.org/ontology/MESH/D009020	MESH	LOOM
http://www.projecthalo.com/aura#Morphine	AURA	LOOM
http://radlex.org/RID/RID45794	RADLEX	LOOM
http://purl.bioontology.org/ontology/RCD/x02LY	RCD	LOOM