Cell Line Ontology

Last uploaded: June 28, 2024
Preferred Name

professional antigen presenting cell
Synonyms

APC

Definitions

A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.

ID

http://purl.obolibrary.org/obo/CL_0000145

comment

Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.

capable of

http://purl.obolibrary.org/obo/GO_0002504

capable of part of

http://purl.obolibrary.org/obo/GO_0002504

functionally related to

http://purl.obolibrary.org/obo/GO_0002504

has_broad_synonym

APC

has_obo_namespace

cell

imported from

http://purl.obolibrary.org/obo/cl.owl

label

professional antigen presenting cell

prefixIRI

CL:0000145

prefLabel

professional antigen presenting cell

textual definition

A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.

subClassOf

http://purl.obolibrary.org/obo/CL_0000738

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CL_0000145 CL SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 UBERON SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 FOVT SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 CHEAR SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 DOID SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 PCL SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 NIFDYS SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 HHEAR SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 DDSS SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 HRA SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 UPHENO SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 KTAO SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 MAXO SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 OBA SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 CL LOOM
http://purl.obolibrary.org/obo/CL_0000145 UBERON LOOM
http://purl.obolibrary.org/obo/CL_0000145 FOVT LOOM
http://purl.obolibrary.org/obo/CL_0000145 CHEAR LOOM
http://purl.obolibrary.org/obo/CL_0000145 DOID LOOM
http://purl.obolibrary.org/obo/CL_0000145 PCL LOOM
http://purl.obolibrary.org/obo/CL_0000145 NIFDYS LOOM
http://purl.obolibrary.org/obo/CL_0000145 HHEAR LOOM
http://purl.obolibrary.org/obo/CL_0000145 DDSS LOOM
http://purl.obolibrary.org/obo/CL_0000145 HRA LOOM
http://purl.obolibrary.org/obo/CL_0000145 UPHENO LOOM
http://purl.obolibrary.org/obo/CL_0000145 NIFSTD LOOM
http://purl.obolibrary.org/obo/CL_0000145 KTAO LOOM
http://purl.obolibrary.org/obo/CL_0000145 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CL_0000145 MAXO LOOM
http://purl.obolibrary.org/obo/CL_0000145 OBA LOOM
http://purl.obolibrary.org/obo/ZFA_0009088 ZFA LOOM
http://purl.obolibrary.org/obo/ZFA_0009088 ZP LOOM
http://purl.org/obo/owl/CL#CL_0000145 BIOMODELS LOOM
http://purl.obolibrary.org/obo/TAO_0009088 TAO LOOM