Preferred Name |
verapamil |
Synonyms |
verapamil verapamilo rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Verapamil verapamilum |
Definitions |
A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine. |
ID |
http://purl.obolibrary.org/obo/CHEBI_9948 |
charge |
0 |
database_cross_reference |
PMID:26504804 HMDB:HMDB0001850 PMID:24577794 Reaxys:2825000 PMID:11142488 PMID:17724247 PMID:18337499 KEGG:C07188 PMID:16545584 Beilstein:2825000 PMID:26046259 PMID:25650380 PMID:11975770 Wikipedia:Verapamil PMID:14681337 PMID:18093581 PMID:24532601 PMID:12454681 CAS:52-53-9 PMID:25968157 PMID:11454724 KEGG:D02356 PMID:8861548 PMID:26567612 DrugBank:DB00661 PMID:25297337 PMID:25331694 PMID:17525564 PMID:11389609 PMID:26553277 PMID:19125880 |
definition |
A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine. |
formula |
C27H38N2O4 |
has part | |
has role |
http://purl.obolibrary.org/obo/CHEBI_62872 http://purl.obolibrary.org/obo/CHEBI_77748 http://purl.obolibrary.org/obo/CHEBI_35703 http://purl.obolibrary.org/obo/CHEBI_38215 http://purl.obolibrary.org/obo/CHEBI_77745 http://purl.obolibrary.org/obo/CHEBI_35674 http://purl.obolibrary.org/obo/CHEBI_38070 http://purl.obolibrary.org/obo/CHEBI_77747 http://purl.obolibrary.org/obo/CHEBI_78298 |
has_exact_synonym |
rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Verapamil |
has_obo_namespace |
chebi_ontology |
has_related_synonym |
verapamil verapamilo verapamilum |
id |
CHEBI:9948 |
in_subset | |
label |
verapamil |
mass |
454.60160 |
monoisotopicmass |
454.28316 |
notation |
CHEBI:9948 |
prefLabel |
verapamil |
treeView | |
subClassOf |