Preferred Name |
Astrocyte |
|
Synonyms |
astrocytic glia |
|
Definitions |
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive. |
|
ID |
http://purl.obolibrary.org/obo/CL_0000127 |
|
comment |
Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive. |
|
altLabel |
astrocytic glia |
|
ccf_ct_isa | ||
ccf_located_in |
http://purl.obolibrary.org/obo/UBERON_0001890 http://purl.obolibrary.org/obo/UBERON_0001898 http://purl.obolibrary.org/obo/UBERON_0002792 http://purl.obolibrary.org/obo/UBERON_0026386 http://purl.obolibrary.org/obo/UBERON_0019264 http://purl.obolibrary.org/obo/UBERON_0031906 http://purl.obolibrary.org/obo/UBERON_0030276 http://purl.obolibrary.org/obo/UBERON_0014638 http://purl.obolibrary.org/obo/UBERON_0029636 |
|
ccf_pref_label |
astrocyte |
|
database_cross_reference |
BTO:0000099 CALOHA:TS-0060 FMA:54537 |
|
definition |
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. |
|
has exact synonym |
astrocytic glia |
|
id |
CL:0000127 |
|
in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas |
|
isDefinedBy | ||
label |
astrocyte |
|
notation |
CL:0000127 |
|
prefLabel |
Astrocyte astrocyte |
|
present_in_taxon | ||
subClassOf |