Preferred Name |
Motor Neuron Disease |
|
Synonyms |
Motor System Disease |
|
ID |
http://bioontology.org/projects/ontologies/birnlex#birnlex_12565 |
|
abbrev | ||
class_or_indiv |
true |
|
definition |
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy ( BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation (MeSH). |
|
external_id_urls |
http://www.nlm.nih.gov/cgi/mesh/2008/MB_cgi?field=uid&term=D016472 |
|
external_ids |
umlsCUI:C0085084|meshUID:D016472 |
|
label |
Motor Neuron Disease |
|
mod_date |
2007-11-18 |
|
preferred_label |
Motor Neuron Disease |
|
prefixIRI |
birnlex_12565 |
|
prefLabel |
Motor Neuron Disease |
|
retired |
false |
|
synonyms |
Motor System Disease |
|
subClassOf |
http://bioontology.org/projects/ontologies/birnlex#birnlex_2086 |