BioModels Ontology

Last uploaded: April 3, 2012
Preferred Name

ethambutol

Synonyms
Definitions

Ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone.

ID

http://purl.obolibrary.org/obo/CHEBI_4877

alternative term

C10H24N2O2

CC[C@@H](CO)NCCN[C@@H](CC)CO

InChI=1S/C10H24N2O2/c1-3-9(7-13)11-5-6-12-10(4-2)8-14/h9-14H,3-8H2,1-2H3/t9-,10-/m0/s1

(+)-S,S-ethambutol

ethambutol

S,S-Ethambutol

InChIKey=AEUTYOVWOVBAKS-UWVGGRQHSA-N

etambutol

(+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine

ethambutolum

(+)-ethambutol

(+)-2,2'-(ethylenediimino)di-1-butanol

(2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol

(S,S)-ethambutol

(2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol

Ethambutol

EMB

definition

Ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone.

has role

http://purl.obolibrary.org/obo/CHEBI_33231

label

ethambutol

prefixIRI

CHEBI:4877

prefLabel

ethambutol

subClassOf

http://purl.obolibrary.org/obo/CHEBI_23981

http://purl.obolibrary.org/obo/CHEBI_31577

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http://purl.obolibrary.org/obo/CHEBI_4877 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4877 HOIP SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4877 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4877 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4877 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4877 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4877 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4877 TXPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4877 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4877 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4877 ODNAE SAME_URI
http://purl.obolibrary.org/obo/XCO_0001158 XCO LOOM
http://purl.obolibrary.org/obo/CHEBI_4877 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_4877 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_4877 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_4877 CHEBI LOOM
http://purl.bioontology.org/ontology/SNMI/C-55240 SNMI LOOM
http://purl.jp/bio/4/id/200906081436639321 IOBC LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00973 COID LOOM
http://purl.obolibrary.org/obo/NCIT_C61755 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0014964 OCHV LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387129004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/ATC/J04AK02 ATC LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00590 OCIMIDO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000701810 PDQ LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147838 ODAE LOOM
http://www.co-ode.org/ontologies/galen#Ethambutol GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.782.258.368.265 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147838 NDFRT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61755 NCIT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016206 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/MESH/D004977 MESH LOOM
http://purl.obolibrary.org/obo/MESH_D004977 BERO LOOM
http://stirdf.jst.go.jp/id/200907028784636170 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#4685 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/LP15625-4 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004977 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_4877 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_4877 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4877 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_4877 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_4877 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4877 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_4877 ODNAE LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008452 LOINC LOOM
http://purl.obolibrary.org/obo/OMIT_0006206 OMIT LOOM
http://purl.obolibrary.org/obo/ARO_3000497 ARO LOOM
http://purl.bioontology.org/ontology/VANDF/4019747 VANDF LOOM
http://www.gamuts.net/entity#ethambutol GAMUTS LOOM
https://go.drugbank.com/drugs/DB00330 MDM LOOM
http://purl.bioontology.org/ontology/CSP/0118-9990 CRISP LOOM
http://purl.bioontology.org/ontology/RXNORM/4110 RXNORM LOOM