Preferred Name |
Tetracycline |
|
Synonyms |
|
|
Definitions |
A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline binds to the 30S ribosomal subunit, interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C865 |
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ALT_DEFINITION |
A drug used to treat bacterial infections. It stops the growth of bacteria by keeping them from making proteins. Tetracycline also binds to new bone tissue and is being studied as a way to detect bone growth. Tetracycline is a type of antibiotic and a type of bone-labeling agent. |
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CAS_Registry |
60-54-8 |
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CHEBI_ID |
CHEBI:27902 |
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Chemical_Formula |
C22H24N2O8 |
|
code |
C865 |
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Contributing_Source |
FDA |
|
definition |
A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline binds to the 30S ribosomal subunit, interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. |
|
FDA_UNII_Code |
F8VB5M810T |
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Has_Salt_Form | ||
in_subset | ||
label |
Tetracycline |
|
Legacy Concept Name |
Tetracycline |
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NSC Number |
108579 |
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Preferred_Name |
Tetracycline |
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prefixIRI |
NCIT:C865 |
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prefLabel |
Tetracycline |
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Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
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UMLS_CUI |
C0039644 |
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subClassOf |