loading...| Preferred Name |
Glioblastoma |
|
| Synonyms |
|
|
| Definitions |
The most malignant astrocytic tumor (WHO grade 4). It is composed of poorly differentiated neoplastic astrocytes and is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation, and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. (Adapted from WHO) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C3058 |
|
| ALT_DEFINITION |
A fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain and spinal cord and has cells that look very different from normal cells. GBM usually occurs in adults and affects the brain more often than the spinal cord. |
|
| code |
C3058 |
|
| Contributing_Source |
Cellosaurus CPTAC CTEP GDC |
|
| definition |
The most malignant astrocytic tumor (WHO grade 4). It is composed of poorly differentiated neoplastic astrocytes and is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation, and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. (Adapted from WHO) |
|
| DesignNote |
Glioblastoma is not an astrocytoma. It is an astrocytic tumor. The latter includes astrocytomas and glioblastomas. However, when an anaplastic astrocytoma progresses to grade IV tumor, it is called a glioblastoma. |
|
| ICD-O-3_Code |
9440/3 |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C138190 http://purl.obolibrary.org/obo/NCIT_C168658 http://purl.obolibrary.org/obo/NCIT_C168656 http://purl.obolibrary.org/obo/NCIT_C168657 http://purl.obolibrary.org/obo/NCIT_C168655 http://purl.obolibrary.org/obo/NCIT_C158520 http://purl.obolibrary.org/obo/NCIT_C102905 http://purl.obolibrary.org/obo/NCIT_C168662 http://purl.obolibrary.org/obo/NCIT_C168661 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C159328 http://purl.obolibrary.org/obo/ncit#oncotree_slim http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C156953 http://purl.obolibrary.org/obo/NCIT_C159335 http://purl.obolibrary.org/obo/NCIT_C126659 http://purl.obolibrary.org/obo/NCIT_C138188 http://purl.obolibrary.org/obo/NCIT_C165258 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C156966 |
|
| Is_Value_For_GDC_Property |
http://purl.obolibrary.org/obo/NCIT_C177615 http://purl.obolibrary.org/obo/NCIT_C178243 http://purl.obolibrary.org/obo/NCIT_C177584 |
|
| label |
Glioblastoma |
|
| Legacy Concept Name |
Glioblastoma |
|
| Maps_To |
Glioblastoma Glioblastoma, NOS Glioblastoma multiforme CNS, glioblastoma (GBM) Spongioblastoma multiforme 01 02 03 04 10 20 62 9440/3 |
|
| Neoplasm_Has_Special_Category | ||
| Neoplastic_Status |
Malignant |
|
| Preferred_Name |
Glioblastoma |
|
| prefixIRI |
NCIT:C3058 |
|
| prefLabel |
Glioblastoma |
|
| Semantic_Type |
Neoplastic Process |
|
| UMLS_CUI |
C0017636 |
|
| subClassOf |
http://purl.obolibrary.org/obo/NCIT_C129325 |