Preferred Name |
Nitrofurantoin |
|
Synonyms |
|
|
Definitions |
A synthetic derivative of imidazolidinedione, Nitrofurantoin inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically as a urinary anti-infective agent against most gram-positive and gram-negative organisms and for long-term suppression of infections. (NCI04) |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C29293 |
|
CAS_Registry |
67-20-9 |
|
CHEBI_ID |
CHEBI:71415 |
|
Chemical_Formula |
C8H6N4O5 |
|
code |
C29293 |
|
Contributing_Source |
FDA |
|
definition |
A synthetic derivative of imidazolidinedione, Nitrofurantoin inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically as a urinary anti-infective agent against most gram-positive and gram-negative organisms and for long-term suppression of infections. (NCI04) |
|
FDA_UNII_Code |
927AH8112L |
|
Has_Salt_Form | ||
in_subset | ||
label |
Nitrofurantoin |
|
Legacy Concept Name |
Nitrofurantoin |
|
NSC Number |
2107 44150 |
|
Preferred_Name |
Nitrofurantoin |
|
prefixIRI |
NCIT:C29293 |
|
prefLabel |
Nitrofurantoin |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0028156 |
|
subClassOf |