Preferred Name |
G Protein-Coupled Receptor |
|
Synonyms |
|
|
Definitions |
Cell surface receptors that are coupled to G-proteins (GTP-binding protein). G-protein coupled receptors are thought to have seven membrane spanning domains and have been divided into 2 subclasses: those in which the binding site is in the extracellular domain for example receptors for glycoprotein hormones, such as thyroid stimulating hormone (TSH) and follicle-stimulating hormone (FSH) and those in which the ligand binding site is likely to be in the plane of the 7 transmembrane domains for example rhodopsin and receptors for small neurotransmitters and hormones for example muscarinic acetylcholine receptor. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C18239 |
|
code |
C18239 |
|
definition |
Cell surface receptors that are coupled to G-proteins (GTP-binding protein). G-protein coupled receptors are thought to have seven membrane spanning domains and have been divided into 2 subclasses: those in which the binding site is in the extracellular domain for example receptors for glycoprotein hormones, such as thyroid stimulating hormone (TSH) and follicle-stimulating hormone (FSH) and those in which the ligand binding site is likely to be in the plane of the 7 transmembrane domains for example rhodopsin and receptors for small neurotransmitters and hormones for example muscarinic acetylcholine receptor. |
|
label |
G Protein-Coupled Receptor |
|
Legacy Concept Name |
G_Protein-Coupled_Receptor |
|
Preferred_Name |
G Protein-Coupled Receptor |
|
prefixIRI |
NCIT:C18239 |
|
prefLabel |
G Protein-Coupled Receptor |
|
Semantic_Type |
Amino Acid, Peptide, or Protein Receptor |
|
UMLS_CUI |
C0682972 |
|
subClassOf |