Preferred Name

busulfan

Synonyms

butane-1,4-diyl dimethanesulfonate

Busulfan

1,4-Dimesyloxybutane

Tetramethylene bis(methanesulfonate)

Myeloleukon

1,4-Dimethanesulfonoxybutane

1,4-Bis(methanesulfonoxy)butane

Leucosulfan

1,4-Butanediol dimethanesulfonate

Bisulfex

Mablin

Mielucin

Misulban

Mitostan

Myleran

busulfan

busulfano

busulfanum

Definitions

A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant.

ID

http://purl.obolibrary.org/obo/CHEBI_28901

charge

0

database_cross_reference

KEGG:C06862

KEGG:D00248

PMID:10523796

PMID:19611402

CAS:55-98-1

Drug_Central:438

PMID:19361744

Reaxys:1791786

DrugBank:DB01008

LINCS:LSM-5388

Beilstein:1791786

Patent:US2917432

Wikipedia:Busulfan

definition

A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant.

formula

C6H14O6S2

has_alternative_id

CHEBI:18936

CHEBI:3225

has_exact_synonym

butane-1,4-diyl dimethanesulfonate

Busulfan

has_functional_parent

http://purl.obolibrary.org/obo/CHEBI_41189

has_obo_namespace

chebi_ontology

has_related_synonym

1,4-Dimesyloxybutane

Tetramethylene bis(methanesulfonate)

Myeloleukon

1,4-Dimethanesulfonoxybutane

1,4-Bis(methanesulfonoxy)butane

Leucosulfan

1,4-Butanediol dimethanesulfonate

Bisulfex

Mablin

Mielucin

Misulban

Mitostan

Myleran

busulfan

busulfano

busulfanum

id

CHEBI:28901

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3

inchikey

COVZYZSDYWQREU-UHFFFAOYSA-N

label

busulfan

mass

246.30200

monoisotopicmass

246.02318

notation

CHEBI:28901

prefLabel

busulfan

RO_0000087

http://purl.obolibrary.org/obo/CHEBI_50905

http://purl.obolibrary.org/obo/CHEBI_35610

http://purl.obolibrary.org/obo/CHEBI_67105

http://purl.obolibrary.org/obo/CHEBI_22333

http://purl.obolibrary.org/obo/CHEBI_50903

smiles

CS(=O)(=O)OCCCCOS(C)(=O)=O

subClassOf

http://purl.obolibrary.org/obo/CHEBI_25223

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