Preferred Name | cisplatin | |
Synonyms |
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Definitions |
A condition in which the main influencing factor is cisplatin, a chemotherapy drug in which two ammine ligands and two chloro ligands are oriented in a cis planar configuration around a central platinum ion. Cisplatin is mutagenic and serves as an anti-cancer drug through its ability to bind to and crosslink DNA, interfering with cell division, triggering DNA repair mechanisms and, in turn, activating apoptosis. |
|
ID |
http://purl.obolibrary.org/obo/XCO_0000398 |
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created_by |
JSmith |
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creation_date |
2014-02-27T15:53:25Z |
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database_cross_reference |
CHEBI:27899 |
|
definition |
A condition in which the main influencing factor is cisplatin, a chemotherapy drug in which two ammine ligands and two chloro ligands are oriented in a cis planar configuration around a central platinum ion. Cisplatin is mutagenic and serves as an anti-cancer drug through its ability to bind to and crosslink DNA, interfering with cell division, triggering DNA repair mechanisms and, in turn, activating apoptosis. |
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has_obo_namespace |
experimental_condition_ontology |
|
id |
XCO:0000398 |
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label |
cisplatin |
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notation |
XCO:0000398 |
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prefLabel |
cisplatin |
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treeView |
http://purl.obolibrary.org/obo/XCO_0000399 |
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subClassOf |
http://purl.obolibrary.org/obo/XCO_0000399 |