loading...| Preferred Name |
Proteinuria |
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| Synonyms |
High Urine Protein Levels |
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| Definitions |
Screening Recommendations: Screen all individuals with SCD, beginning by age 10, for proteinuria. If the result is negative, repeat screening annually. If the result is positive, perform a first morning void urine albumin-creatinine ratio and if abnormal, consult with or refer to a renal specialist. Increased amounts of any protein (including albumin) in the urine - typically more than 300mg in a 24hr period. |
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| ID |
http://purl.obolibrary.org/obo/SCDO_0000932 |
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| rdfs:comment |
Screening Recommendations: Screen all individuals with SCD, beginning by age 10, for proteinuria. If the result is negative, repeat screening annually. If the result is positive, perform a first morning void urine albumin-creatinine ratio and if abnormal, consult with or refer to a renal specialist. |
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| curator note |
Suggest update to description in HPO. |
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| database cross reference |
HP:0000093 |
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| dc:source |
http://www.nhlbi.nih.gov/health-pro/guidelines/sickle-cell-disease-guidelines |
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| definition |
Increased amounts of any protein (including albumin) in the urine - typically more than 300mg in a 24hr period. |
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| definition source | ||
| diagnosed using measurement |
http://purl.obolibrary.org/obo/CMO_0000057 http://purl.obolibrary.org/obo/SCDO_0001207 http://purl.obolibrary.org/obo/SCDO_0001209 |
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| existence in other ontologies |
Suggest update to description |
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| has age of onset |
In sickle cell disease, overt proteinuria (distinguised from albuminuria) may be noted in childhood although less common (4.5% in ages 2-21 [Wigfall 2000] v. 26% in adults [Guasch 2006]). |
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| has disease stage |
At most severe form - lead to nephrotic syndrome. |
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| hasExactSynonym |
High Urine Protein Levels |
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| in guideline |
http://purl.obolibrary.org/obo/SCDO_1000150 http://purl.obolibrary.org/obo/SCDO_1000153 http://purl.obolibrary.org/obo/SCDO_1000152 http://purl.obolibrary.org/obo/SCDO_1000144 http://purl.obolibrary.org/obo/SCDO_1000149 http://purl.obolibrary.org/obo/SCDO_1000148 |
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| is caused by |
Caused by a variety of kidney diseases, including sickle cell disease, diabetes, glomerular disease, arteriosclerosis. |
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| is characterised by |
Elevated amounts of protein in the urine - typically greater than 300mg in 24 hrs. |
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| prefixIRI |
SCDO:0000932 |
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| prefLabel |
Proteinuria |
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| rdfs:label |
Proteinuria |
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| treated with | ||
| subClassOf |