loading...| Preferred Name | alcohol | |
| Synonyms |
absolute ethanol ethyl alcohol ethanol methylcarbinol |
|
| Definitions |
A volatile liquid prepared by fermentation of certain carbohydrates. Alcohol acts as a central nervous system (CNS) depressant, a diuretic, and a disinfectant. Although the exact mechanism of CNS depression is unknown, alcohol may act by inhibiting the opening of calcium channels, mediated by the binding of the inhibitory neurotransmitter gamma-amino butyric acid (GABA) to GABA-A receptors, or through inhibitory actions at N-methyl-D-aspartate (NMDA)-type glutamate receptors. Alcohol inhibits the production of antidiuretic hormone, thereby producing diuresis that may lead to dehydration. This agent kills organisms by denaturing their proteins. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2190" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2190" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000446576 |
|
| altLabel |
absolute ethanol ethyl alcohol ethanol methylcarbinol |
|
| CAS Registry |
64-17-5 8000-16-6 |
|
| cui |
C0001962 |
|
| DATE FIRST PUBLISHED |
2005-09-09 |
|
| Date last modified |
2017-12-13 |
|
| definition |
A volatile liquid prepared by fermentation of certain carbohydrates. Alcohol acts as a central nervous system (CNS) depressant, a diuretic, and a disinfectant. Although the exact mechanism of CNS depression is unknown, alcohol may act by inhibiting the opening of calcium channels, mediated by the binding of the inhibitory neurotransmitter gamma-amino butyric acid (GABA) to GABA-A receptors, or through inhibitory actions at N-methyl-D-aspartate (NMDA)-type glutamate receptors. Alcohol inhibits the production of antidiuretic hormone, thereby producing diuresis that may lead to dehydration. This agent kills organisms by denaturing their proteins. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2190" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2190" NCI Thesaurus) |
|
| NCI ID |
C2190 |
|
| notation |
CDR0000446576 |
|
| NSC Code |
85228 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
alcohol |
|
| tui |
T109 T121 |