Preferred Name | acute myeloid leukemia | |
Synonyms |
AML - Acute Myeloid Leukemia acute myelogenous leukemia leukemia, acute nonlymphocytic ANLL acute myeloblastic leukemia leukemia, acute myeloid acute myelogenous leukemias AML |
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Definitions |
A clonal expansion of myeloid blasts in the bone marrow, blood or other tissues. The classification of acute myeloid leukemias (AMLs) encompasses four major categories: 1) AML with recurrent genetic abnormalities 2) AML with multilineage dysplasia 3) Therapy-related AML 4) AML not otherwise categorized. The required bone marrow or peripheral blood blast percentage for the diagnosis of AML has been recently reduced from 30% (French-American-British [FAB] classification) to 20% (WHO classification). (WHO, 2001) Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C3171" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C3171" NCI Thesaurus) |
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ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000043424 |
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altLabel |
AML - Acute Myeloid Leukemia acute myelogenous leukemia leukemia, acute nonlymphocytic ANLL acute myeloblastic leukemia leukemia, acute myeloid acute myelogenous leukemias AML |
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Associated genetic condition | ||
cui |
C0023467 |
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Date last modified |
2012-03-21 |
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definition |
A clonal expansion of myeloid blasts in the bone marrow, blood or other tissues. The classification of acute myeloid leukemias (AMLs) encompasses four major categories: 1) AML with recurrent genetic abnormalities 2) AML with multilineage dysplasia 3) Therapy-related AML 4) AML not otherwise categorized. The required bone marrow or peripheral blood blast percentage for the diagnosis of AML has been recently reduced from 30% (French-American-British [FAB] classification) to 20% (WHO classification). (WHO, 2001) Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C3171" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C3171" NCI Thesaurus) |
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Legacy PDQ ID |
818 |
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NCI ID |
C3171 |
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notation |
CDR0000043424 |
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ORIG STY |
Neoplasm diagnosis |
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prefLabel |
acute myeloid leukemia |
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tui |
T191 |
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subClassOf |