Preferred Name | Hypoparathyroidism | |
Synonyms |
Parathyroid, underactivity of Hypoparathyroidism [Disease/Finding] Hypoparathyroidism (disorder) Hypoparathyroidism, unspecified Low parathyroid hormone Hypoparathyroidism, idiopathic (subtype) Deficiency of parathyrin Deficiency of PTH hypoparathyroidism Deficiency of parathyroid hormone |
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Definitions |
[CSP Definition]: Condition produced by greatly reduced function of the parathyroids possibly due to autoimmune disease or genetic factors, or by the removal of those bodies; lack of parathyroid hormone leads to a fall in plasma calcium level, which may result in increase neuromuscular excitability and ultimately tetany followed by a rise in plasma phosphate level. [NCIt Definition]: An endocrine disorder characterized by decreased production of parathyroid hormone by the parathyroid glands. It is usually caused by damage of the parathyroid glands during head and neck surgery. Signs and symptoms include muscle cramps, abdominal pain, dry skin, brittle nails, cataracts, tetany, and convulsions. [CTCAE Definition]: A disorder characterized by a decrease in production of parathyroid hormone by the parathyroid glands. [GARD Definition]: Hypoparathyroidism is is an endocrine disorder in which the parathyroid glands in the neck do not produce enough parathyroid hormone (PTH). Common signs and symptoms include abdominal pain, brittle nails, cataracts, dry hair and skin, muscle cramps, tetany, pain in the face, legs, and feet, seizures, tingling sensation, and weakened tooth enamel (in children). It may be caused by injury to the parathyroid glands (e.g., during surgery). Other causes, include low blood magnesium levels, a side effect of radioactive iodine treatment for hyperthyroidism, metabolic alkalosis, DiGeorge syndrome, and type I polyglandular autoimmune syndrome. The goal of treatment is to restore the calcium and mineral balance in the body. - this information is from GARD/ORDR/NCATS. [NICHD Definition]: Decreased production or secretion of parathyroid hormone by the parathyroid gland, resulting in hypocalcemia due to decreased release of calcium and phosphate from bone matrix, decreased renal calcium reabsorption, and decreased renal production of 1,25-dihydroxyvitamin D-3, which decreases intestinal absorption of calcium. Hypoparathyroidism is also associated with hyperphosphatemia as a result of hypophosphaturia. [HPO Definition]: A condition caused by a deficiency of parathyroid hormone characterized by hypocalcemia and hyperphosphatemia. [HPO:probinson] [MSH Definition]: A condition caused by a deficiency of PARATHYROID HORMONE (or PTH). It is characterized by HYPOCALCEMIA and hyperphosphatemia. Hypocalcemia leads to TETANY. The acquired form is due to removal or injuries to the PARATHYROID GLANDS. The congenital form is due to mutations of genes, such as TBX1; (see DIGEORGE SYNDROME); CASR encoding CALCIUM-SENSING RECEPTOR; or PTH encoding parathyroid hormone. |
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ID |
http://pat.nichd.nih.gov/maternalconditions/C0020626 |
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Definition |
[CSP Definition]: Condition produced by greatly reduced function of the parathyroids possibly due to autoimmune disease or genetic factors, or by the removal of those bodies; lack of parathyroid hormone leads to a fall in plasma calcium level, which may result in increase neuromuscular excitability and ultimately tetany followed by a rise in plasma phosphate level. [NCIt Definition]: An endocrine disorder characterized by decreased production of parathyroid hormone by the parathyroid glands. It is usually caused by damage of the parathyroid glands during head and neck surgery. Signs and symptoms include muscle cramps, abdominal pain, dry skin, brittle nails, cataracts, tetany, and convulsions. [CTCAE Definition]: A disorder characterized by a decrease in production of parathyroid hormone by the parathyroid glands. [GARD Definition]: Hypoparathyroidism is is an endocrine disorder in which the parathyroid glands in the neck do not produce enough parathyroid hormone (PTH). Common signs and symptoms include abdominal pain, brittle nails, cataracts, dry hair and skin, muscle cramps, tetany, pain in the face, legs, and feet, seizures, tingling sensation, and weakened tooth enamel (in children). It may be caused by injury to the parathyroid glands (e.g., during surgery). Other causes, include low blood magnesium levels, a side effect of radioactive iodine treatment for hyperthyroidism, metabolic alkalosis, DiGeorge syndrome, and type I polyglandular autoimmune syndrome. The goal of treatment is to restore the calcium and mineral balance in the body. - this information is from GARD/ORDR/NCATS. [NICHD Definition]: Decreased production or secretion of parathyroid hormone by the parathyroid gland, resulting in hypocalcemia due to decreased release of calcium and phosphate from bone matrix, decreased renal calcium reabsorption, and decreased renal production of 1,25-dihydroxyvitamin D-3, which decreases intestinal absorption of calcium. Hypoparathyroidism is also associated with hyperphosphatemia as a result of hypophosphaturia. [HPO Definition]: A condition caused by a deficiency of parathyroid hormone characterized by hypocalcemia and hyperphosphatemia. [HPO:probinson] [MSH Definition]: A condition caused by a deficiency of PARATHYROID HORMONE (or PTH). It is characterized by HYPOCALCEMIA and hyperphosphatemia. Hypocalcemia leads to TETANY. The acquired form is due to removal or injuries to the PARATHYROID GLANDS. The congenital form is due to mutations of genes, such as TBX1; (see DIGEORGE SYNDROME); CASR encoding CALCIUM-SENSING RECEPTOR; or PTH encoding parathyroid hormone. |
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External Source |
https://ncim.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&code=C0020626 |
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Label |
Hypoparathyroidism |
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notation |
C0020626 |
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PAT ID |
C0020626 |
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prefLabel |
Hypoparathyroidism |
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Sub Class Of | ||
Synonyms |
Parathyroid, underactivity of Hypoparathyroidism [Disease/Finding] Hypoparathyroidism (disorder) Hypoparathyroidism, unspecified Low parathyroid hormone Hypoparathyroidism, idiopathic (subtype) Deficiency of parathyrin Deficiency of PTH hypoparathyroidism Deficiency of parathyroid hormone |