Ontology of Adverse Events

Last uploaded: September 3, 2022
Preferred Name

cerebrospinal fluid
Synonyms

liquor cerebrospinalis

spinal fluid

CSF

cerebral spinal fluid

Definitions

A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord.

ID

http://purl.obolibrary.org/obo/UBERON_0001359

database_cross_reference

http://linkedlifedata.com/resource/umls/id/C0007806

http://uri.neuinfo.org/nif/nifstd/birnlex_1798

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12692

http://en.wikipedia.org/wiki/Cerebrospinal_fluid

MESH:A12.207.268

EV:0100311

ENVO:02000029

UMLS:C0007806

GAID:1181

MA:0002503

MAT:0000499

VHOG:0001278

TAO:0002184

CALOHA:TS-0130

EHDAA2:0004441

EFO:0000329

ZFA:0001626

FMA:20935

BTO:0000237

definition

A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord.

develops_from

http://purl.obolibrary.org/obo/UBERON_0002307

external_definition

Portion of organism substance that is a clear fluid that occupies the subarachnoid space and the ventricular system around and inside the brain.[TAO]

external_ontology_notes

the FMA def states that this is subarachnoid spaces only. ZFA def states subarachnoid spaces and brain ventricles, but not SC (and has part_of to brain). Circulation: It circulates from the lateral ventricles to the foramen of Monro (Interventricular foramen), third ventricle, aqueduct of Sylvius (Cerebral aqueduct), fourth ventricle, foramen of Magendie (Median aperture) and foramina of Luschka (Lateral apertures), subarachnoid space over brain and spinal cord. It should be noted that the CSF moves in a pulsatile manner throughout the CSF system with nearly zero net flow. CSF is reabsorbed into venous sinus blood via arachnoid granulations.

has_exact_synonym

CSF

cerebral spinal fluid

has_obo_namespace

uberon

has_related_synonym

liquor cerebrospinalis

spinal fluid

homology_notes

In vertebrates, at early stages of Central Nervous System (CNS) development, the architecture of the brain primordium reveals the presence of the cavity of brain vesicles, which is filled by Embryonic Cerebro-Spinal Fluid (E-CSF). (...) Rat and chick E-CSF proteomes are similar, although rat is more complex in certain groups of proteins, e.g., apolipoproteins, which may be involved in the control of neural diversity, and has soluble enzymes present, just like adult human CSF, but unlike chick E-CSF, revealing phylogenetic brain differences between these groups of vertebrates.[uncertain][VHOG]

id

UBERON:0001359

imported from

http://purl.obolibrary.org/obo/uberon.owl

in_subset

http://purl.obolibrary.org/obo/uberon#uberon_slim

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

http://purl.obolibrary.org/obo/uberon#vertebrate_core

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

cerebrospinal fluid

located_in

http://purl.obolibrary.org/obo/UBERON_0005281

notation

UBERON:0001359

prefLabel

cerebrospinal fluid

treeView

http://purl.obolibrary.org/obo/UBERON_0002307

subClassOf

http://purl.obolibrary.org/obo/UBERON_0007779

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Delete Mapping To Ontology Source
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http://purl.obolibrary.org/obo/UBERON_0001359 ORCS SAME_URI
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