loading...| Preferred Name | cisplatin | |
| Synonyms |
[PtCl2(NH3)2] Platamine Neoplatin Briplatin Platinol cis-diamminedichloroplatinum Randa cis-[PtCl2(NH3)2] cis-dichlorodiammineplatinum(II) cis-platin cisplatin Peyrone's salt cisplatinum cis-Diamminedichloroplatinum(II) cis-diammineplatinum(II) dichloride Cismaplat cisplatino Lederplatin cis-DDP CDDP cisplatine Platinex Peyrone's chloride Cisplatin (SP-4-2)-diamminedichloridoplatinum cis-diamminedichloridoplatinum(II) (SP-4-2)-diamminedichloroplatinum cis-diamminedichloroplatinum(II) |
|
| Definitions |
A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups). |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_27899 |
|
| alternative label |
[PtCl2(NH3)2] Platamine Neoplatin Briplatin Platinol cis-diamminedichloroplatinum Randa cis-[PtCl2(NH3)2] cis-dichlorodiammineplatinum(II) cis-platin cisplatin Peyrone's salt cisplatinum cis-Diamminedichloroplatinum(II) cis-diammineplatinum(II) dichloride Cismaplat cisplatino Lederplatin cis-DDP CDDP cisplatine Platinex Peyrone's chloride Cisplatin (SP-4-2)-diamminedichloridoplatinum cis-diamminedichloridoplatinum(II) (SP-4-2)-diamminedichloroplatinum cis-diamminedichloroplatinum(II) |
|
| charge |
0 |
|
| database_cross_reference |
PMID:23651576 PMID:10883661 PMID:23554447 KEGG:C06911 PMID:28494534 PMID:23604226 PMID:12935404 PMID:1855275 MolBase:25 Patent:DE2329485 PMID:18472761 HMDB:HMDB0014656 Wikipedia:Cisplatin CAS:15663-27-1 Gmelin:2519 KEGG:D00275 Reaxys:11324567 PMID:12537968 PMID:16327988 PMID:12831510 DrugBank:DB00515 Patent:DE2318020 MetaCyc:CPD0-1392 |
|
| definition |
A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups). |
|
| formula |
H6Cl2N2Pt Cl2H6N2Pt |
|
| has characteristic |
http://purl.obolibrary.org/obo/CHEBI_47868 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_50684 http://purl.obolibrary.org/obo/CHEBI_25435 http://purl.obolibrary.org/obo/CHEBI_173085 |
|
| has exact synonym |
Cisplatin (SP-4-2)-diamminedichloridoplatinum cis-diamminedichloridoplatinum(II) (SP-4-2)-diamminedichloroplatinum cis-diamminedichloroplatinum(II) |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_47868 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_50684 http://purl.obolibrary.org/obo/CHEBI_25435 http://purl.obolibrary.org/obo/CHEBI_173085 |
|
| has_alternative_id |
CHEBI:3722 CHEBI:23314 |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
[PtCl2(NH3)2] Platamine Neoplatin Briplatin Platinol cis-diamminedichloroplatinum Randa cis-[PtCl2(NH3)2] cis-dichlorodiammineplatinum(II) cis-platin cisplatin Peyrone's salt cisplatinum cis-Diamminedichloroplatinum(II) cis-diammineplatinum(II) dichloride Cismaplat cisplatino Lederplatin cis-DDP CDDP cisplatine Platinex Peyrone's chloride |
|
| id |
CHEBI:27899 |
|
| in_subset | ||
| inchi |
InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2 |
|
| inchikey |
LXZZYRPGZAFOLE-UHFFFAOYSA-L |
|
| label |
cisplatin |
|
| mass |
300.04452 |
|
| monoisotopicmass |
298.95560 |
|
| notation |
CHEBI:27899 |
|
| note |
A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups). |
|
| preferred label |
cisplatin |
|
| prefLabel |
cisplatin |
|
| smiles |
[H][N]([H])([H])[Pt](Cl)(Cl)[N]([H])([H])[H] |
|
| subClassOf |