National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Glycine
Synonyms

Aminoethanoic acid

GLYCINE

Gly

Glycine

Definitions

A non-essential, non-polar, non-optical, glucogenic amino acid. Glycine, an inhibitory neurotransmitter in the CNS, triggers chloride ion influx via ionotropic receptors, thereby creating an inhibitory post-synaptic potential. In contrast, this agent also acts as a co-agonist, along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is an important component and precursor for many macromolecules in the cells.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C524

ALT_DEFINITION

Amino acid with side chain -H.

CAS_Registry

56-40-6

CHEBI_ID

CHEBI:15428

Chemical_Formula

C2H5NO2

code

C524

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

FDA

DEFINITION

A non-essential, non-polar, non-optical, glucogenic amino acid. Glycine, an inhibitory neurotransmitter in the CNS, triggers chloride ion influx via ionotropic receptors, thereby creating an inhibitory post-synaptic potential. In contrast, this agent also acts as a co-agonist, along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is an important component and precursor for many macromolecules in the cells.

FDA_UNII_Code

TE7660XO1C

FULL_SYN

Aminoethanoic acid

GLYCINE

Gly

Glycine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C79999

label

Glycine

Legacy Concept Name

Glycine

NCI_Drug_Dictionary_ID

41347

NSC Number

25936

PDQ_Closed_Trial_Search_ID

41347

PDQ_Open_Trial_Search_ID

41347

Preferred_Name

Glycine

prefixIRI

Thesaurus:C524

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0017890

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68442

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29596

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http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Glycine APANEUROCLUSTER LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Glycine APAONTO LOOM
http://purl.obolibrary.org/obo/UPa_UPC00037 UPA LOOM
http://www.projecthalo.com/aura#Glycine AURA LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01425 MIO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 NPOKB LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 OCMR LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 DTO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 BIPON LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 CDNO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 PECO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 ONSTR LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 MAXO LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 ZP LOOM
http://purl.obolibrary.org/obo/CHEBI_15428 OBA LOOM
http://purl.obolibrary.org/obo/SO_0001443 SO LOOM
http://purl.obolibrary.org/obo/SO_0001443 SO LOOM
http://purl.obolibrary.org/obo/SO_0001443 NIFSTD LOOM
https://go.drugbank.com/drugs/DB00145 MDM LOOM
http://localhost/plosthes.2017-1#3150 PLOSTHES LOOM
http://www.co-ode.org/ontologies/amino-acid/2006/05/18/amino-acid.owl#G AMINO-ACID LOOM
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http://purl.obolibrary.org/obo/IMR_0100118 HOIP LOOM
http://purl.obolibrary.org/obo/IMR_0100118 TXPO LOOM
http://stirdf.jst.go.jp/id/200907040891624249 IOBC LOOM
http://purl.obolibrary.org/obo/OMIT_0007187 OMIT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021314 PMAPP-PMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0017890 OCHV LOOM
http://www.drugbank.ca/drugs/DB00145 FTC LOOM
http://purl.obolibrary.org/obo/NCIT_C524 BERO LOOM
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http://purl.jp/bio/4/id/200906049264128183 IOBC LOOM
http://www.co-ode.org/ontologies/galen#Glycine GALEN LOOM
http://purl.bioontology.org/ontology/ATC/B05CX03 ATC LOOM
http://purl.org/sig/ont/fma/fma82753 FMA LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000041347 PDQ LOOM
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http://sbmi.uth.tmc.edu/ontology/ochv#C0522461 OCHV LOOM