National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Phenylalanine
Synonyms

L-Phenylalanine

PHENYLALANINE

Phenylalanine

2-Amino-3-phenyl-pronanoic acid

Phe

Definitions

An essential aromatic amino acid in humans (provided by food), Phenylalanine plays a key role in the biosynthesis of other amino acids and is important in the structure and function of many proteins and enzymes. Phenylalanine is converted to tyrosine, used in the biosynthesis of dopamine and norepinephrine neurotransmitters. The L-form of Phenylalanine is incorporated into proteins, while the D-form acts as a painkiller. Absorption of ultraviolet radiation by Phenylalanine is used to quantify protein amounts. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29601

ALT_DEFINITION

Amino acid with side chain -CH2C6H5.

CAS_Registry

63-91-2

CHEBI_ID

CHEBI:17295

Chemical_Formula

C9H11NO2

code

C29601

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

CTRP

FDA

DEFINITION

An essential aromatic amino acid in humans (provided by food), Phenylalanine plays a key role in the biosynthesis of other amino acids and is important in the structure and function of many proteins and enzymes. Phenylalanine is converted to tyrosine, used in the biosynthesis of dopamine and norepinephrine neurotransmitters. The L-form of Phenylalanine is incorporated into proteins, while the D-form acts as a painkiller. Absorption of ultraviolet radiation by Phenylalanine is used to quantify protein amounts. (NCI04)

Display_Name

Phenylalanine

Essential_Amino_Acid

Y

FDA_UNII_Code

47E5O17Y3R

FULL_SYN

L-Phenylalanine

PHENYLALANINE

Phenylalanine

2-Amino-3-phenyl-pronanoic acid

Phe

INFOODS

PHE_G

label

Phenylalanine

Legacy Concept Name

Phenylalanine

Macronutrient

Y

Nutrient

Y

Preferred_Name

Phenylalanine

prefixIRI

Thesaurus:C29601

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0031453

Unit

g

USDA_ID

508

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68442

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Delete Mapping To Ontology Source
http://purl.jp/bio/4/id/200906097520504516 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LP70160-4 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9610 OCHV LOOM
http://www.co-ode.org/ontologies/galen#Phenylalanine GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010649 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D010649 BERO LOOM
http://www.projecthalo.com/aura#Phenylalanine AURA LOOM
http://purl.bioontology.org/ontology/LNC/LP15792-2 LOINC LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Phenylalanine APAONTO LOOM
http://purl.obolibrary.org/obo/SO_0001441 SO LOOM
http://purl.obolibrary.org/obo/SO_0001441 SO LOOM
http://purl.obolibrary.org/obo/SO_0001441 NIFSTD LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021273 PMAPP-PMO LOOM
http://www.co-ode.org/ontologies/amino-acid/2006/05/18/amino-acid.owl#F AMINO-ACID LOOM
http://purl.bioontology.org/ontology/NDDF/003542 NDDF LOOM
http://purl.obolibrary.org/obo/NCIT_C29601 BERO LOOM
http://purl.bioontology.org/ontology/SNMI/F-64410 SNMI LOOM
http://purl.bioontology.org/ontology/CSP/0777-7571 CRISP LOOM
http://purl.obolibrary.org/obo/SIBO_0000205 SIBO LOOM
http://purl.obolibrary.org/obo/SIBO_0000205 SIBO LOOM
https://go.drugbank.com/drugs/DB00120 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.072.050.685 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/8156 RXNORM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146984 NDFRT LOOM
http://localhost/plosthes.2017-1#205 PLOSTHES LOOM
http://purl.org/obo/owlapi/fma#FMA_82754 BIOMODELS LOOM
http://purl.bioontology.org/ontology/MESH/D010649 MESH LOOM
http://purl.bioontology.org/ontology/RCD/X807U RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.142.666 RH-MESH LOOM
http://purl.org/sig/ont/fma/fma82754 FMA LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 UBERON LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 OCMR LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 PCL LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 BIPON LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 CDNO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 FB-CV LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 PECO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 ONSTR LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 MAXO LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 ZP LOOM
http://purl.obolibrary.org/obo/CHEBI_28044 OBA LOOM
http://purl.bioontology.org/ontology/VANDF/4018673 VANDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/63004003 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003552 LOINC LOOM
http://purl.jp/bio/10/gmo/GMO_001793 GMO LOOM
http://purl.obolibrary.org/obo/OMIT_0011637 OMIT LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_28044 NPO LOOM
http://stirdf.jst.go.jp/id/200907080892620320 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0031453 OCHV LOOM