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Homeostasis imbalance process ontology
| Preferred Name | EC 5.99.1.2 (DNA topoisomerase) inhibitor | |
| Synonyms |
type I DNA topoisomerase inhibitors EC 5.99.1.2 inhibitor EC 5.99.1.2 inhibitors EC 5.99.1.2 (topoisomerase I) inhibitor topoisomerase I (EC 5.99.1.2) inhibitors DNA topoisomerase inhibitors type I DNA topoisomerase inhibitor DNA topoisomerase inhibitor topoisomerase I (EC 5.99.1.2) inhibitor EC 5.99.1.2 (DNA topoisomerase) inhibitors topoisomerase I inhibitors EC 5.99.1.2 (topoisomerase I) inhibitors topoisomerase I inhibitor |
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| Definitions |
A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_50276 |
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| definition |
A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA.
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| has_related_synonym |
type I DNA topoisomerase inhibitors EC 5.99.1.2 inhibitor EC 5.99.1.2 inhibitors EC 5.99.1.2 (topoisomerase I) inhibitor topoisomerase I (EC 5.99.1.2) inhibitors DNA topoisomerase inhibitors type I DNA topoisomerase inhibitor DNA topoisomerase inhibitor topoisomerase I (EC 5.99.1.2) inhibitor EC 5.99.1.2 (DNA topoisomerase) inhibitors topoisomerase I inhibitors EC 5.99.1.2 (topoisomerase I) inhibitors topoisomerase I inhibitor
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| label |
EC 5.99.1.2 (DNA topoisomerase) inhibitor
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| prefixIRI |
CHEBI:50276
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| prefLabel |
EC 5.99.1.2 (DNA topoisomerase) inhibitor
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