loading...| Preferred Name |
Stevens-Johnson syndrome |
|
| Synonyms |
severe cutaneous adverse reaction, susceptibility to Stevens-Johnson syndrome, susceptibility to toxic Epidermal necrolysis, susceptibility to hypersensitivity syndrome, carbamazepine-induced, susceptibility to erythema multiforme major Dermatostomatitis, Stevens Johnson type Stevens-Johnson syndrome Stevens Johnson syndrome |
|
| Definitions |
A variant of bullous erythema multiforme. It ranges from mild skin and mucous membrane lesions to a severe, sometimes fatal systemic disorder. Ocular symptoms include ulcerative conjunctivitis, keratitis, iritis, uveitis, and sometimes blindness. The cause of the disease is unknown. Stevens-Johnson syndrome is a limited form of toxic epidermal necrolysis characterized by destruction and detachment of the skin epithelium and mucous membranes involving less than 10% of the body surface area. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0004276 |
|
| closeMatch | ||
| database_cross_reference |
MedDRA:10015218 NCIt:C79484 SNOMEDCT:73442001 MedDRA:10042033 DOID:0050426 UMLS:C0038325 ICD9:695.13 ICD9:695.15 ICD9:695.12 ICD10CM:L51.1 OMIM:608579 MeSH:D013262 MESH:D013262 SCTID:73442001 NANDO:1200245 NANDO:2100290 NANDO:2201006 NCIT:C79484 Orphanet:36426 icd11.foundation:450167795 GARD:7700 MONDO:0018229 |
|
| definition |
A variant of bullous erythema multiforme. It ranges from mild skin and mucous membrane lesions to a severe, sometimes fatal systemic disorder. Ocular symptoms include ulcerative conjunctivitis, keratitis, iritis, uveitis, and sometimes blindness. The cause of the disease is unknown. Stevens-Johnson syndrome is a limited form of toxic epidermal necrolysis characterized by destruction and detachment of the skin epithelium and mucous membranes involving less than 10% of the body surface area. |
|
| exactMatch |
http://purl.bioontology.org/ontology/ICD10CM/L51.1 http://identifiers.org/snomedct/73442001 http://identifiers.org/mesh/D013262 http://purl.obolibrary.org/obo/Orphanet_36426 http://purl.obolibrary.org/obo/NCIT_C79484 |
|
| gwas_trait |
true |
|
| has_exact_synonym |
Dermatostomatitis, Stevens Johnson type Stevens-Johnson syndrome Stevens Johnson syndrome |
|
| has_related_synonym |
severe cutaneous adverse reaction, susceptibility to Stevens-Johnson syndrome, susceptibility to toxic Epidermal necrolysis, susceptibility to hypersensitivity syndrome, carbamazepine-induced, susceptibility to erythema multiforme major |
|
| id |
EFO:0004276 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#nord_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_clinical_subtype |
|
| label |
Stevens-Johnson syndrome |
|
| notation |
EFO:0004276 |
|
| preferred label |
Stevens-Johnson syndrome |
|
| prefLabel |
Stevens-Johnson syndrome |
|
| term editor |
Dani Welter |
|
| subClassOf | ||
| excluded_subClassOf |