Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

D-Phenylalanine
Synonyms
Definitions

The synthetic dextro isomer of phenylalanine, an essential amino acid with anti-depressant and analgesic activities. D-Phenylalanine is converted into tyrosine and tyrosine in turn is converted into L-dopa, norepinephrine, and epinephrine, three key neurotransmitters. As a result this agent is associated with elevated levels of the neurotransmitters dopamine and norepinephrine in the brain, which may alleviate symptoms of depression. In addition, as an inhibitor of enkephalinase, which metabolizes endorphins, D-phenylalanine may be used to treat chronic pain through blocking the break down of endorphins (natural pain killers).
ID

http://purl.obolibrary.org/obo/NCIT_C61715
CAS_Registry

673-06-3
CHEBI_ID

CHEBI:16998
Chemical_Formula

C9H11NO2
code

C61715
Contributing_Source

FDA
definition

The synthetic dextro isomer of phenylalanine, an essential amino acid with anti-depressant and analgesic activities. D-Phenylalanine is converted into tyrosine and tyrosine in turn is converted into L-dopa, norepinephrine, and epinephrine, three key neurotransmitters. As a result this agent is associated with elevated levels of the neurotransmitters dopamine and norepinephrine in the brain, which may alleviate symptoms of depression. In addition, as an inhibitor of enkephalinase, which metabolizes endorphins, D-phenylalanine may be used to treat chronic pain through blocking the break down of endorphins (natural pain killers).
FDA_UNII_Code

032K16VRCU
in_subset

http://purl.obolibrary.org/obo/NCIT_C63923
label

D-Phenylalanine
Legacy Concept Name

D-Phenylalanine
Preferred_Name

D-Phenylalanine
prefixIRI

NCIT:C61715
prefLabel

D-Phenylalanine
Semantic_Type

Pharmacologic Substance
UMLS_CUI

C0771172
subClassOf

http://purl.obolibrary.org/obo/NCIT_C231
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