Preferred Name

Aminobenzoic Acid
Synonyms
Definitions

An organic acid with UV absorption and antifibrotic properties. When exposed to light, aminobenzoic acid (para-aminobenzoic acid or PABA) absorbs UV light and emits excess energy via a photochemical reaction that may cause damage to DNA. Because DNA defects contribute to skin cancer, aminobenzoic acid is no longer widely used in sunscreen formulations. Aminobenzoic acid may also increase oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity to promote the degradation of serotonin, which in excess, may lead to fibrotic changes.

ID

http://purl.obolibrary.org/obo/NCIT_C61634

ALT_DEFINITION

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Bacteria that live in the intestines need aminobenzoic acid to survive. Aminobenzoic acid is found in grains and foods from animals. It is being studied as a radiosensitizer (a substance that makes tumor cells more sensitive to radiation therapy) and in the treatment of certain skin disorders.

CAS_Registry

150-13-0

CHEBI_ID

CHEBI:30753

Chemical_Formula

C7H7NO2

code

C61634

Contributing_Source

FDA

definition

An organic acid with UV absorption and antifibrotic properties. When exposed to light, aminobenzoic acid (para-aminobenzoic acid or PABA) absorbs UV light and emits excess energy via a photochemical reaction that may cause damage to DNA. Because DNA defects contribute to skin cancer, aminobenzoic acid is no longer widely used in sunscreen formulations. Aminobenzoic acid may also increase oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity to promote the degradation of serotonin, which in excess, may lead to fibrotic changes.

FDA_UNII_Code

TL2TJE8QTX

Has_Salt_Form

http://purl.obolibrary.org/obo/NCIT_C1736

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Aminobenzoic Acid

Legacy Concept Name

Aminobenzoic_Acid

Preferred_Name

Aminobenzoic Acid

prefixIRI

NCIT:C61634

prefLabel

Aminobenzoic Acid

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0552314

subClassOf

http://purl.obolibrary.org/obo/NCIT_C26017

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http://purl.obolibrary.org/obo/CHEBI_22495 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 FB-CV LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 PECO LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 MAXO LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 ZP LOOM
http://purl.obolibrary.org/obo/CHEBI_22495 OBA LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61634 NCIT LOOM
http://purl.bioontology.org/ontology/SNMI/C-93210 SNMI LOOM
http://purl.bioontology.org/ontology/NDDF/002325 NDDF LOOM
http://purl.bioontology.org/ontology/NDDF/002338 NDDF LOOM
http://purl.bioontology.org/ontology/NDDF/001006 NDDF LOOM
http://purl.bioontology.org/ontology/ATC/D02BA01 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/782612003 SNOMEDCT LOOM
http://www.co-ode.org/ontologies/galen#AminobenzoicAcid GALEN LOOM
https://go.drugbank.com/drugs/DB02362 MDM LOOM