Preferred Name | Aminobenzoic Acid | |
Synonyms |
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Definitions |
An organic acid with UV absorption and antifibrotic properties. When exposed to light, aminobenzoic acid (para-aminobenzoic acid or PABA) absorbs UV light and emits excess energy via a photochemical reaction that may cause damage to DNA. Because DNA defects contribute to skin cancer, aminobenzoic acid is no longer widely used in sunscreen formulations. Aminobenzoic acid may also increase oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity to promote the degradation of serotonin, which in excess, may lead to fibrotic changes. |
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ID |
http://purl.obolibrary.org/obo/NCIT_C61634 |
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ALT_DEFINITION |
A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Bacteria that live in the intestines need aminobenzoic acid to survive. Aminobenzoic acid is found in grains and foods from animals. It is being studied as a radiosensitizer (a substance that makes tumor cells more sensitive to radiation therapy) and in the treatment of certain skin disorders. |
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CAS_Registry |
150-13-0 |
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CHEBI_ID |
CHEBI:30753 |
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Chemical_Formula |
C7H7NO2 |
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code |
C61634 |
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Contributing_Source |
FDA |
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definition |
An organic acid with UV absorption and antifibrotic properties. When exposed to light, aminobenzoic acid (para-aminobenzoic acid or PABA) absorbs UV light and emits excess energy via a photochemical reaction that may cause damage to DNA. Because DNA defects contribute to skin cancer, aminobenzoic acid is no longer widely used in sunscreen formulations. Aminobenzoic acid may also increase oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity to promote the degradation of serotonin, which in excess, may lead to fibrotic changes. |
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FDA_UNII_Code |
TL2TJE8QTX |
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Has_Salt_Form | ||
in_subset | ||
label |
Aminobenzoic Acid |
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Legacy Concept Name |
Aminobenzoic_Acid |
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Preferred_Name |
Aminobenzoic Acid |
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prefixIRI |
NCIT:C61634 |
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prefLabel |
Aminobenzoic Acid |
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Semantic_Type |
Pharmacologic Substance |
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UMLS_CUI |
C0552314 |
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subClassOf |