Preferred Name | Leukemia | |
Synonyms |
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Definitions |
A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years. |
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ID |
http://purl.obolibrary.org/obo/NCIT_C3161 |
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ALT_DEFINITION |
Cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream. A progressive, proliferative disease of blood cells, originating from myeloid or lymphoid stem cells. A cancer of the blood or bone marrow that is characterized by increased production of abnormal blood cells. |
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code |
C3161 |
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Contributing_Source |
CDISC CPTAC CTEP CTRP GDC MedDRA NICHD |
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definition |
A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years. |
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Display_Name |
Leukemia |
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ICD-O-3_Code |
9800/3 |
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in_subset |
http://purl.obolibrary.org/obo/NCIT_C138190 http://purl.obolibrary.org/obo/NCIT_C168658 http://purl.obolibrary.org/obo/NCIT_C168656 http://purl.obolibrary.org/obo/NCIT_C168657 http://purl.obolibrary.org/obo/NCIT_C168655 http://purl.obolibrary.org/obo/NCIT_C77526 http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C158520 http://purl.obolibrary.org/obo/NCIT_C102905 http://purl.obolibrary.org/obo/NCIT_C168662 http://purl.obolibrary.org/obo/NCIT_C168661 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C175324 http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C158035 http://purl.obolibrary.org/obo/NCIT_C158034 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C118464 http://purl.obolibrary.org/obo/NCIT_C126659 http://purl.obolibrary.org/obo/NCIT_C138188 http://purl.obolibrary.org/obo/NCIT_C88025 http://purl.obolibrary.org/obo/NCIT_C118168 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C156966 http://purl.obolibrary.org/obo/NCIT_C99147 |
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Is_Value_For_GDC_Property |
http://purl.obolibrary.org/obo/NCIT_C178243 http://purl.obolibrary.org/obo/NCIT_C2991 |
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label |
Leukemia |
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Legacy Concept Name |
Leukemia |
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Maps_To |
Other leukaemias of specified cell type Leukemias, NOS Other specified leukaemias Leukaemia of unspecified cell type Leukaemia, unspecified Leukemia, unspecified not having achieved remission Leukemia of unspecified cell type Unspecified leukemia without mention of having achieved remission Other specified leukemia Other specified leukemias Other specified leukemias not having achieved remission Other leukemia of unspecified cell type without mention of having achieved remission Leukemia, NOS Other leukemia of unspecified cell type Unspecified leukemia 9800/3 Leukemia |
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Neoplastic_Status |
Malignant |
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Preferred_Name |
Leukemia |
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prefixIRI |
NCIT:C3161 |
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prefLabel |
Leukemia |
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Semantic_Type |
Neoplastic Process |
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UMLS_CUI |
C0023418 |
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subClassOf |