Preferred Name

Malignant Neoplasm
Synonyms
Definitions

A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas.

ID

http://purl.obolibrary.org/obo/NCIT_C9305

ALT_DEFINITION

A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Malignant cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of malignancy. Carcinoma is a malignancy that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a malignancy that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a malignancy that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are malignancies that begin in the cells of the immune system. Central nervous system cancers are malignancies that begin in the tissues of the brain and spinal cord.

A group of diseases in which abnormal cells divide without control, invade nearby tissues and may also spread to other parts of the body through the blood and lymph systems.

Uncontrolled growth of abnormal cells with potential for metastatic spread.

A general term for autonomous tissue growth exhibiting morphologic features of malignancy (e.g. severe atypia, nuclear pleomorphism, tumor cell necrosis, abnormal mitoses, tissue invasiveness) and for which the transformed cell type has not been specifically identified.

code

C9305

Contributing_Source

CDISC

CPTAC

CTRP

FDA

GDC

MedDRA

NICHD

database_cross_reference

IMDRF:E1801

definition

A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas.

Display_Name

Malignant Neoplasm

ICD-O-3_Code

8000/3

in_subset

http://purl.obolibrary.org/obo/NCIT_C168658

http://purl.obolibrary.org/obo/NCIT_C168656

http://purl.obolibrary.org/obo/NCIT_C168657

http://purl.obolibrary.org/obo/NCIT_C168655

http://purl.obolibrary.org/obo/NCIT_C62596

http://purl.obolibrary.org/obo/NCIT_C77526

http://purl.obolibrary.org/obo/NCIT_C90259

http://purl.obolibrary.org/obo/NCIT_C158520

http://purl.obolibrary.org/obo/NCIT_C168662

http://purl.obolibrary.org/obo/NCIT_C168661

http://purl.obolibrary.org/obo/NCIT_C54450

http://purl.obolibrary.org/obo/NCIT_C19752

http://purl.obolibrary.org/obo/NCIT_C177537

http://purl.obolibrary.org/obo/ncit#oncotree_slim

http://purl.obolibrary.org/obo/NCIT_C156952

http://purl.obolibrary.org/obo/NCIT_C156954

http://purl.obolibrary.org/obo/NCIT_C156953

http://purl.obolibrary.org/obo/NCIT_C158034

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C118464

http://purl.obolibrary.org/obo/NCIT_C88025

http://purl.obolibrary.org/obo/NCIT_C118168

http://purl.obolibrary.org/obo/NCIT_C157711

http://purl.obolibrary.org/obo/NCIT_C156966

http://purl.obolibrary.org/obo/NCIT_C99147

http://purl.obolibrary.org/obo/NCIT_C61410

Is_Value_For_GDC_Property

http://purl.obolibrary.org/obo/NCIT_C178243

http://purl.obolibrary.org/obo/NCIT_C177621

http://purl.obolibrary.org/obo/NCIT_C17103

http://purl.obolibrary.org/obo/NCIT_C16457

http://purl.obolibrary.org/obo/NCIT_C176985

label

Malignant Neoplasm

Legacy Concept Name

Malignant_Neoplasm

Maps_To

Malignant neoplasm of other and ill-defined sites: Lower limb

Neoplasm, malignant

Malignant neoplasm, primary site unknown, so stated

Tumor, malignant, NOS

Other malignant neoplasm of unspecified site

Malignant neoplasm of other and ill-defined sites

Unclassified tumor, malignant

Malignant neoplasm, without specification of site

Malignant neoplasm, unspecified

Malignant neoplasm of other specified sites

Malignant neoplasm of other and ill-defined sites: Overlapping lesion of other and ill-defined sites

Malignant neoplasm without specification of site

8000/3

Cancer

Malignancy

Neoplastic_Status

Malignant

Preferred_Name

Malignant Neoplasm

prefixIRI

NCIT:C9305

prefLabel

Malignant Neoplasm

Semantic_Type

Neoplastic Process

UMLS_CUI

C1861853

subClassOf

http://purl.obolibrary.org/obo/NCIT_C7062

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