Preferred Name

notochord
Synonyms

notochorda

embryonic notocord

notocord

Definitions

A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube. The notochord appears early in embryogeny and plays an important role in promoting or organizing the embryonic development of nearby structures. In most adult chordates the notochord disappears or becomes highly modified. In some non-vertebrate chordates and fishes the notochord persists as a laterally flexible but incompressible skeletal rod that prevents telescopic collapse of the body during swimming[TOLWEB]

ID

http://purl.obolibrary.org/obo/UBERON_0002328

comment

The notochord appears early in embryogeny and plays an important role in promoting or organizing the embryonic development of nearby structures. In most adult chordates the notochord disappears or becomes highly modified. In some non-vertebrate chordates and fishes the notochord persists as a laterally flexible but incompressible skeletal rod that prevents telescopic collapse of the body during swimming[TOLWEB]

contributor

https://github.com/cmungall

https://github.com/wdahdul

database_cross_reference

VHOG:0000199

MESH:D009672

ZFA:0000135

UMLS:C0028439

VSAO:0000032

EHDAA2:0001277

NCIT:C12463

XAO:0000055

AAO:0000327

BTO:0001768

TAO:0000135

Wikipedia:Notochord

http://evolution.berkeley.edu/evolibrary/images/history/notochords.jpg

EMAPA:16191

MAT:0000281

SCTID:308820002

CALOHA:TS-0690

EHDAA:1241

EHDAA:6021

EV:0100002

FMA:85521

GAID:1311

definition

A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube.

depicted_by

http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png

develops_from

http://purl.obolibrary.org/obo/UBERON_0006267

http://purl.obolibrary.org/obo/UBERON_0004880

dorsal to

http://purl.obolibrary.org/obo/UBERON_0001555

existence starts during

http://purl.obolibrary.org/obo/UBERON_0000068

existence starts during or after

http://purl.obolibrary.org/obo/UBERON_0000068

has_exact_synonym

embryonic notocord

notocord

hasOBONamespace

uberon

hasRelatedSynonym

notochorda

id

UBERON:0002328

in taxon

http://purl.obolibrary.org/obo/NCBITaxon_7711

inSubset

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

notochord

notation

UBERON:0002328

only in taxon

http://purl.obolibrary.org/obo/NCBITaxon_7711

part_of

http://purl.obolibrary.org/obo/NCBITaxon_6072

http://purl.obolibrary.org/obo/UBERON_0011137

prefLabel

notochord

produces

http://purl.obolibrary.org/obo/PR_000014841

treeView

http://purl.obolibrary.org/obo/UBERON_0006267

http://purl.obolibrary.org/obo/UBERON_0004880

http://purl.obolibrary.org/obo/NCBITaxon_6072

http://purl.obolibrary.org/obo/UBERON_0011137

UBPROP_0000001

Slender rod of fibrous connective tissue surrounding a core of fluid-filled cells of mesodermal origin; it lies above the gut and directly beneath the spinal cord. The notochord is present during early development and in a few cases it is retained through life; however, usually the notochord is replaced by the vertebral column.[AAO]

Avascular multi-tissue structure composed of large vacuolated epithelial cells (chordablasts) and perichordal fibrous tissue.[VSAO]

Rod-like principal supportive element of the embryo and larva, present in the midline just ventral to the neural tube, and differentiating during the segmentation period to form large vacuolated epithelial cells and a surrounding a sheath of fibrous and elastic layers. Layering of the sheath may differ in structure, thickness and development among groups; in cypriniforms there are actually three very thin layers to the sheath. A functional, well developed notochord is present throughout life in certain basal fish groups but not in cypriniforms. Kimmel et al, 1995.[TAO]

UBPROP_0000002

relationship type change: differentiates_from mesoderm (AAO:0000304) CHANGED TO: develops_from mesoderm (UBERON:0000926)[AAO]

UBPROP_0000003

(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (3) a stiff, longitudinal rod of turgid cells along the dorsal part of the body that is called a notochord (...).[well established][VHOG]

UBPROP_0000007

notochordal

UBPROP_0000011

In between vertebra the notochord becomes the nucleus pulposus, under it degenerates, and at anterior end in some species its tissue merges with some of the cranial bones.. Some organisms retain a post-embryonic notochord.

ventral to

http://purl.obolibrary.org/obo/UBERON_0001049

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000481

http://purl.obolibrary.org/obo/UBERON_0000062

http://purl.obolibrary.org/obo/UBERON_0004120

http://purl.obolibrary.org/obo/UBERON_0004121

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/UBERON_0002328 CL SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 OAE SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 PDRO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 UBERON SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 CLO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 INBANCIDO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 OVAE SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 OHPI SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 GCBO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 CCONT SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 FOVT SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 OCMR SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 OPMI SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 RBO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 EFO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 XPO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 PCL SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 MONDO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 PATO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 NIFDYS SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 BERO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 EFO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 NBO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 HHEAR SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 ODAE SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 UPHENO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 OCVDAE SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 ECAO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 KTAO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 MAXO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 FNS-H SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 NMDCO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 OBA SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002328 CL LOOM
http://purl.obolibrary.org/obo/EMAPA_16191 EMAPA LOOM
http://purl.obolibrary.org/obo/EHDAA_6021 EHDAA LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12463 NCIT LOOM
http://purl.obolibrary.org/obo/OMIT_0010691 OMIT LOOM
http://purl.obolibrary.org/obo/EHDAA2_0001277 EHDAA2 LOOM
http://purl.bioontology.org/ontology/SNMI/T-F6410 SNMI LOOM
http://purl.org/obo/owlapi/fma#FMA_85521 BIOMODELS LOOM
http://purl.obolibrary.org/obo/VHOG_0000199 VHOG LOOM
http://purl.obolibrary.org/obo/PhfumiA_0000665 PHFUMIADO LOOM
http://purl.obolibrary.org/obo/EHDA_1861 EHDA LOOM
http://purl.obolibrary.org/obo/EHDA_4319 EHDA LOOM
http://purl.obolibrary.org/obo/HaauraA_0000665 HAAURAADO LOOM
http://bioportal.bioontology.org/ontologies/FISHO#FISHO_0000045 FISHO LOOM
http://purl.obolibrary.org/obo/TAO_0000135 TAO LOOM
http://purl.obolibrary.org/obo/MFO_0002120 MFO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009672 RH-MESH LOOM
http://purl.obolibrary.org/obo/BTO_0001768 BTO LOOM
http://purl.obolibrary.org/obo/MAT_0000281 MAT LOOM
http://purl.obolibrary.org/obo/EHDA_3329 EHDA LOOM
http://purl.obolibrary.org/obo/MooculA_0000665 MOOCULADO LOOM
http://purl.obolibrary.org/obo/EHDA_6022 EHDA LOOM
http://purl.bioontology.org/ontology/MESH/D009672 MESH LOOM
http://purl.obolibrary.org/obo/HaroreA_0000665 HAROREADO LOOM
http://purl.obolibrary.org/obo/VSAO_0000032 VSAO LOOM
http://purl.obolibrary.org/obo/VSAO_0000032 TAO LOOM
http://www.projecthalo.com/aura#Notochord AURA LOOM
http://purl.obolibrary.org/obo/CisaviA_0000665 CISAVIADO LOOM
http://purl.obolibrary.org/obo/EHDA_9520 EHDA LOOM
http://purl.obolibrary.org/obo/EHDA_8342 EHDA LOOM
http://purl.jp/bio/4/id/200906083217385171 IOBC LOOM
http://purl.obolibrary.org/obo/NCIT_C12463 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0028439 OCHV LOOM
http://purl.obolibrary.org/obo/EHDAA_1241 EHDAA LOOM
http://purl.obolibrary.org/obo/XAO_0000055 XPO LOOM
http://purl.obolibrary.org/obo/XAO_0000055 XAO LOOM
http://purl.obolibrary.org/obo/CiinteA_0000665 CIINTEADO LOOM
http://purl.obolibrary.org/obo/MooccuA_0000665 MOOCCUADO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00000048 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A16.660 RH-MESH LOOM
http://purl.obolibrary.org/obo/MoocciA_0000665 MOOCCIADO LOOM
http://purl.obolibrary.org/obo/AMPHX_1000070 AMPHX LOOM
http://purl.org/sig/ont/fma/fma85521 FMA LOOM
http://purl.obolibrary.org/obo/EHDA_7133 EHDA LOOM
http://purl.obolibrary.org/obo/EHDA_1242 EHDA LOOM
http://purl.obolibrary.org/obo/ZFA_0000135 ZFA LOOM
http://purl.obolibrary.org/obo/ZFA_0000135 ZP LOOM
http://purl.obolibrary.org/obo/PhmammA_0000665 PHMAMMADO LOOM
http://purl.obolibrary.org/obo/EHDA_10615 EHDA LOOM
http://purl.obolibrary.org/obo/EHDA_2536 EHDA LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 OAE LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 PDRO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 UBERON LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 CLO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 INBANCIDO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 OVAE LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 OHPI LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 GCBO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 CCONT LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 FOVT LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 OCMR LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 OPMI LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 RBO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 EFO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 XPO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 PCL LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 PATO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 NIFDYS LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 GO-PLUS LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 EFO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 NBO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 HHEAR LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 ODAE LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 UPHENO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 OCVDAE LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 NIFSTD LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 ECAO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 KTAO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 MAXO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 FNS-H LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 NMDCO LOOM
http://purl.obolibrary.org/obo/UBERON_0002328 OBA LOOM