Experimental Conditions Ontology

Last uploaded: December 9, 2019
Preferred Name

spironolactone

Synonyms

CHEBI:9241

DB00421

Definitions

Spironolactone is a potassium sparing diuretic like eplerenone that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered. It is indicated to treat a number of conditions including heart failure, deem, hyperaldosteronism, adrenal hyperplasia, hypertension, and nephrotic syndrome.

ID

http://purl.obolibrary.org/obo/XCO_0000627

created_by

sjwang

creation_date

2019-07-24T14:33:14Z

definition

Spironolactone is a potassium sparing diuretic like eplerenone that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered. It is indicated to treat a number of conditions including heart failure, deem, hyperaldosteronism, adrenal hyperplasia, hypertension, and nephrotic syndrome.

has_exact_synonym

CHEBI:9241

DB00421

has_obo_namespace

experimental_condition_ontology

id

XCO:0000627

label

spironolactone

notation

XCO:0000627

prefLabel

spironolactone

treeView

http://purl.obolibrary.org/obo/XCO_0000122

subClassOf

http://purl.obolibrary.org/obo/XCO_0000122

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http://purl.bioontology.org/ontology/RCD/b43.. RCD LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C840 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C840 NCIT LOOM
http://purl.bioontology.org/ontology/SNMI/C-72420 SNMI LOOM
http://purl.jp/bio/4/id/200906028579154843 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LP16280-7 LOINC LOOM
http://purl.bioontology.org/ontology/CSP/2794-2536 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.745.745.855 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D013148 MESH LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#spironolactone FASTO LOOM
http://www.ifomis.org/acgt/1.0#Spironolactone ACGT-MO LOOM
http://purl.bioontology.org/ontology/UATC/C03DA01 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.540.679 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003227 LOINC LOOM
http://www.drugbank.ca/drugs/DB00421 FTC LOOM
http://purl.bioontology.org/ontology/VANDF/4017881 VANDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146234 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013148 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 NIFSTD LOOM
http://www.co-ode.org/ontologies/galen#Spironolactone GALEN LOOM
http://purl.bioontology.org/ontology/RXNORM/9997 RXNORM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387078006 SNOMEDCT LOOM
http://bmi.utah.edu/ontologies/hfontology/C0037982 HFO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039444 PDQ LOOM
http://stirdf.jst.go.jp/id/200907023665510166 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0037982 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#11637 OCHV LOOM