loading...| Preferred Name |
spironolactone |
|
| Synonyms |
DB00421 |
|
| Definitions |
Any condition in which the main influencing factor isspironolactone, a potassium-sparing diuretic that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. Spironolactone is indicated to treat a number of conditions including heart failure, edema, hyperaldosteronism, adrenal hyperplasia, hypertension, and nephrotic syndrome. |
|
| ID |
http://purl.obolibrary.org/obo/XCO_0000627 |
|
| created_by |
sjwang |
|
| creation_date |
2019-07-24T14:33:14Z |
|
| database_cross_reference |
CHEBI:9241 |
|
| definition |
Any condition in which the main influencing factor isspironolactone, a potassium-sparing diuretic that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. Spironolactone is indicated to treat a number of conditions including heart failure, edema, hyperaldosteronism, adrenal hyperplasia, hypertension, and nephrotic syndrome. |
|
| has_exact_synonym |
DB00421 |
|
| has_obo_namespace |
experimental_condition_ontology |
|
| id |
XCO:0000627 |
|
| label |
spironolactone |
|
| notation |
XCO:0000627 |
|
| prefLabel |
spironolactone |
|
| treeView | ||
| subClassOf |