Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

pronephric glomerulus

Synonyms

glomus

pronephric glomera

pronephric glomus

pronephric glomeruli

corpuscle

glomera

glomerulus of pronephros

Definitions

The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment.

ID

http://purl.obolibrary.org/obo/UBERON_0004739

database_cross_reference

AAO:0011049

SCTID:360548001

VHOG:0001237

XAO:0000318

TAO:0001557

ZFA:0001557

definition

The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment.

develops_from

http://purl.obolibrary.org/obo/UBERON_0007128

has exact synonym

glomerulus of pronephros

has related synonym

pronephric glomera

pronephric glomus

pronephric glomeruli

corpuscle

glomera

has_alternative_id

UBERON:0004191

has_narrow_synonym

glomus

has_obo_namespace

uberon

IAO_0000232

a glomus differs from a glomerulus in that each vascular glomus services several tubules

id

UBERON:0004739

label

pronephric glomerulus

notation

UBERON:0004739

part_of

http://purl.obolibrary.org/obo/UBERON_0002120

prefixIRI

UBERON:0004739

prefLabel

pronephric glomerulus

treeView

http://purl.obolibrary.org/obo/UBERON_0002120

http://purl.obolibrary.org/obo/UBERON_0007128

UBPROP_0000001

Paired highly vascularized portion of the pronephros. Left and right glomeruli are fused at the midline. Begins to function between 40 and 48hpf. Drummond, 2000.[TAO]

UBPROP_0000003

The teleost pronephros shares many essential features with the amphibian pronephros including its derivation from mesoderm associated with the coelom and the derivation of the glomerular blood supply from the medial dorsal aorta. However, unlike the pronephros of amphibians, which have an external glomus and tubules with nephrostomes open to the coelom, the mature teleost pronephros has no connection to the body cavity and instead functions as a closed system (reference 1); This variation in nephron types [with external glomeruli that open into the coelom and with internal glomeruli that do not connect with the coelom] and their pattern of distribution suggest an evolutionary sequence. Ancestral craniates probably had an external glomerulus and nephrostomes, as do the first few to develop in very primitive craniates. (...) The mechanism would become more efficient as the coelomic recess into which each glomerulus discharged became a part of the tubule, that is, grew around the glomerulus as a renal capsule. The glomerulus becomes internal. The nephrostomes were lost during subsequent evolution, leaving the type of renal tubule found in most vertebrates (reference 2).[well established][VHOG]

UBPROP_0000012

GO treats glomus and pronephric glomerulus differently

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000074

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