Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

Schwannoma

Synonyms

Schwannomas

Neurilemmoma

Schwann cell tumour

Neurolemmoma

Schwann cell tumor

Neurinoma

Definitions

A benign nerve sheath tumor composed of Schwann cells. Glial cells are cells that support nerve cells. Schwann cells wrap around the axon to form the myelin sheath. Schwann cells are involved in many important aspects of peripheral nerve biology; the conduction of nervous impulses along axons, nerve development and regeneration, trophic support for neurons, production of the nerve extracellular matrix and presentation of antigens to T-lymphocytes. Charcot-Marie-Tooth disease (CMT), Guillain-Barre syndrome (GBS), schwannomatosis and chronic inflammatory demyelinating polyneuropathy (CIDP) are all neuropathies involving Schwann cells.

ID

http://purl.obolibrary.org/obo/HP_0100008

comment

Glial cells are cells that support nerve cells. Schwann cells wrap around the axon to form the myelin sheath. Schwann cells are involved in many important aspects of peripheral nerve biology; the conduction of nervous impulses along axons, nerve development and regeneration, trophic support for neurons, production of the nerve extracellular matrix and presentation of antigens to T-lymphocytes. Charcot-Marie-Tooth disease (CMT), Guillain-Barre syndrome (GBS), schwannomatosis and chronic inflammatory demyelinating polyneuropathy (CIDP) are all neuropathies involving Schwann cells.

creation date

2010-05-14T09:13:07Z

creator

https://orcid.org/0009-0006-4530-3154

database_cross_reference

UMLS:C0027809

SNOMEDCT_US:985004

MSH:D009442

SNOMEDCT_US:404022001

definition

A benign nerve sheath tumor composed of Schwann cells.

has exact synonym

Neurilemmoma

Schwann cell tumour

Neurolemmoma

Schwann cell tumor

Neurinoma

has related synonym

Schwannomas

id

HP:0100008

label

Schwannoma

notation

HP:0100008

prefLabel

Schwannoma

subClassOf

http://purl.obolibrary.org/obo/HP_0100007

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